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目的：分析并探讨原发性高血压患者尿微量白蛋白和冠状动脉狭窄性病变程度的关系。方法：选择2010 年8 月至2013 年8 月符合条件的患者按照MAU 阳性与否分为阳性组和阴性组各98 例，分别记录并比较尿微量白蛋白、冠状动脉造影情况及 Gensini积分。结果：①阳性组与阴性组患者在性别、年龄、病程、吸烟史、饮酒史、高血脂症史、血肌酐水平比较差异无统计学意义（P＞0.05）。②两组患者收缩压、舒张压、脉压及脉压指数比较，差异无统计学意义（P＞0.05）。③阳性组相比阴性组冠状动脉造影阳性率高，双支及三支冠脉病变率亦高，差异有统计学意义（P＜0.05）；且阳性组Gensini积分显著高于阴性组（P＜0.05）。结论：原发性高血压伴有MAU阳性患者存在相对更严重的冠状动脉狭窄性病变，通过检测MAU指标有助于及时判断患者病情并指导治疗方案。

英文摘要:

Objective:To analyze and investigate the relationship between microalbuminuria and primary stenotic coronary lesions in patients with hypertension.Methods:We chose eligible patients fromAugust 2010 to August 2013 and divided theminto MAU positive and negative group with 98 cases in each group. We recorded and compared the urinary albumin, coronary angiography and Gensini scores of the two groups.Results:① There was no significant difference between positive group and negative group in the gender, age, disease duration, smoking history, drinking history, history of hyperlipidemia, serumcreatinine level (P> 0.05). ② There was no significant difference between two groups in the systolic blood pressure, diastolic blood pressure, pulse pressure and pulse pressure index (P>0.05). ③Compared with the negative group, the positive group's positive rates of coronary angiography, and three double vessel coronary artery disease rates were higher and the difference was statistically significant (P <0.05). Gensini scores of positive group was significantly higher than that of the negative group (P<0.05).Conclusion:There is a more severe coronary artery stenosis on essential hypertensionaccompaniedMAU, andtimelydetectionMAUindicators canhelpdetermine the patient'sconditionandinstruct the treatment.

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