| 李雅丽 邢英 哈力达·木沙 木胡牙提·乌拉斯汗.代谢综合征与非酒精性脂肪肝临床特征的关系[J].现代生物医学进展英文版,2014,14(22):4298-4300. |
| 代谢综合征与非酒精性脂肪肝临床特征的关系 |
| The Relationship Between Metabolic Syndrome and Clinical Features ofNon-alcoholic Fatty Liver Diseas |
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| DOI： |
| 中文关键词: 临床特征 超声 脂肪肝 危险因素 代谢综合征 |
| 英文关键词: Clinical features Ultrasound Fatty liver disease Risk factors Metabolic syndrome |
| 基金项目:新疆医科大学第一附属医院自然科学基金（2013ZRZD07） |
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| 中文摘要: |
| 目的：探讨代谢综合征（metabolic syndrome, MS）与非酒精性脂肪肝(non-alcoholic fatty liver disease，NAFLD)临床特征之间
的相关性。方法：从我院2012 年1月-2014 年2 月健康体检资料中抽选326 例经超声确诊为NAFLD 的患者，作为NAFLD 组，并
随机抽选335 例无脂肪肝患者作为对照组；观察两组患者间的临床特征，并采用Logistic 回归分析MS 与NAFLD 临床特征之间
的相关性。结果：NAFLD 组患者体重指数（BMI）、血压、丙氨酸氨基转移酶（ALT）、空腹血糖（FBG）、血尿酸(UA)、高密度脂蛋白
（HDL-C）、甘油三酯（TG）、天冬氨酸氨基转移酶（AST)水平显著高于对照组（P<0.05）：两组间低密度脂蛋白（LDL-C）、总胆固醇
（TC）比较无显著性（P＞0.05）。NAFLD 组中MS、血脂及糖代谢异常、肥胖以及高血压的检出率明显高于对照组(P<0.05)。经Logistic
回归分析显示，NAFLD、BMI、TG、HDL-C、高血压及血糖是MS的独立危险因素。结论：NAFLD 患者中存在MS的各种组分
聚集特征，MS患病率明显升高，NAFLD 是MS 的独立危险因素之一，因此MS与NAFLD 关系密切。 |
| 英文摘要: |
| Objective:To investigate the relationship between metabolic syndrome and clinical features of non-alcoholic fatty liver
disease.Methods:326 patients with NAFLD diagnosed via ultrasound in physical examination data from January 2012 to February
2012 were selected as the NAFLD group, and 335 patients without fatty liver were randomly selected as the control group.Clinical features
between two groups of patients were observed, and the correlation between MS and NAFLD clinical features was analyzed by the
Logistic regression analysis.Results:In NAFLD group, body mass index (BMI), blood pressure, alanine aminotransferase (ALT), fasting
blood glucose (FBG), blood uric acid (UA), high-density lipoprotein (HDL- C), triglyceride (TG), aspartate aminotransferase (AST) were
significantly higher than those of the control group (P<0.05), there was no significant differences in low density lipoprotein cholesterol
(LDL - C), total cholesterol (TC) between the two groups (P>0.05). In NAFLD group, the detection rates of MS, abnormal blood lipid,
abnormal glucose metabolism, obesity and hypertension were much higher than those of the control group (P<0.05). The Logistic regression
analysis showed that NAFLD, BMI, TG, HDL - C, high blood pressure and blood sugar were independent risk factors of MS.Conclusion:There are various and gathered characteristics components in patients with NAFLD, and the prevalence of MS increased significantly.
NAFLD is one of the independent risk factors of MS, so MS is closely associated with NAFLD. |
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