| 许文静 樊绮云 张学真 曾慧倩 伍颖恒.胎儿中晚孕期产前超声筛查胎儿畸形的临床价值[J].现代生物医学进展英文版,2014,14(21):4144-4146. |
| 胎儿中晚孕期产前超声筛查胎儿畸形的临床价值 |
| Clinical Value of Ultrasound on the Prenatal Diagnosis of Fetal Malformationin Middle and Late Pregnancy |
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| DOI： |
| 中文关键词: 中晚孕期 产前超声筛查 胎儿畸形 临床价值 |
| 英文关键词: Late pregnancy Prenatal screening Fetal malformation Clinical value |
| 基金项目: |
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| 中文摘要: |
| 目的：分析胎儿中晚孕期产前超声筛查胎儿畸形的临床价值。方法：选取我院2011 年1 月到2013 年1 月间胎儿早孕期超
声检测正常孕妇1240 例，于胎儿中孕期（孕21～25 周）和晚孕期（孕31～35 周）各再进行一次超声检测工作，用Excel 表进行统
计分析，分类归纳统计胎儿畸形分类及各类畸形超声检出时间。结果：1240 例胎儿早期超声检测正常孕妇中，胎儿中孕期检测显
示胎儿畸形16 例，检出率1.3%；其中中枢神经畸形3 例，心脏畸形1 例，前腹壁畸形2 例，泌尿系统畸形1 例，骨骼以及四肢畸形
2 例，双胎畸形2 例，消化系统畸形2 例，胎儿肿瘤1 例，胎儿水肿1 例，指趾异常1 例，胎儿晚孕期检测显示有畸形3 例，检出率
为0.24%，分别为面部畸形1 例，指趾异常1 例，心脏畸形1 例。这19 例胎儿均证实为畸形胎儿。胎儿中孕期漏诊3 例，漏诊率
15.8%（3/19）。结论：超声检查是产前诊断胎儿畸形的重要诊断方法，诊断率高，安全性大，但部分胎儿畸形在中孕期超声仍未能诊
断，所以对胎儿晚孕期再次行超声筛查工作，尤其注意对胎儿颜面部、心脏，颅脑，四肢等器官仔细的扫描，可有效提高畸形胎儿
检测率，减少相应畸形的漏诊，为产科医生临床确诊和处理提供有效参考，具有极高的临床价值，同时可减少出生缺陷的发生，配
合国家人口系统完成出生缺陷一级预防工作。 |
| 英文摘要: |
| Objective:To analyze the value of ultrasound technology on the diagnosis of the fetal malformation for women at the
middle and late pregnancy.Methods:1240 cases who were diagnosed by ultrasound in early pregnancy in our hospital from January 2011
to January 2013 were chosen. Subsequent ultrasounds were performed in middle pregnancy (from 21~25 weeks) and late pregnancy
(from 31~35 weeks) separately, in which malformations were detected, classified systematically and grouped following checked
pregnancy week.Results:16 fetal malformation cases were detected in middle pregnancy, the rate of detection was 1.3%. 2 central
nervous malformation, 1 cardiac malformation, 2 abdominal wall malformation, 1 genitourinary malformation, 2 skeletal malformation，2
twins malformation, 2 gastrointestinal malformation, 1 fetal neoplasm, 1 fetal edema, 1 toes malformation. Three fetal malformation cases
were detected in late pregnancy, the rate of detection was 0.24%. All these cases were confirmed by induced or post partum. Three cases
were misdiagnosed in middle pregnancy, the missed diagnosis rate was 15.8%(3/19).Conclusion:Ultrasound is the most important
method to detect fetal malformation before delivery, it has high detect value and it is safe. To perform ultrasound screening again in
middle and late pregnancy can effectively improve the detection rate of fetal malformations. It can provide the effective references for
clinical diagnosis and treatment and has a high clinical value. |
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