| 欧美贤 李水军 刘罡一 贾晶莹 余琛.VD缺乏相关疾病及其合理补充的临床意义[J].现代生物医学进展英文版,2014,14(19):3798-3800. |
| VD缺乏相关疾病及其合理补充的临床意义 |
| A SystemReview of the Critical Role of Vitamin D in the ClinicalImplications of Vitamin D Deficiency |
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| DOI： |
| 中文关键词: 维生素D 疾病 佝偻病 骨质疏松 流行病学 |
| 英文关键词: Vitamin D Diseases Rickets rachitis Osteoporosis Epidemiology |
| 基金项目:上海市徐汇区中心医院科研基金（2012XHXH02） |
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| 中文摘要: |
| 众所周知，人体内维生素D 水平与少年佝偻病和老年骨质疏松直接相关。最近大量流行病学证据还表明，维生素D（VD）缺
乏是多种自身免疫性疾病，癌症，心血管疾病，抑郁症，老年痴呆症，感染性疾病，肌肉骨骼功能下降等的危险因素之一。另外，胰
岛素抵抗，高血压和高胆固醇血症也与维生素D缺乏有关。因此，合理补充维生素D 可以降低多种疾病风险，并对心血管疾病的
风险有益。本文系根据已有的研究结论，阐述维生素D 水平与多种临床疾病之间的关联，并对人体血清VD 浓度合理监测及合理
补充的临床意义做一综述。 |
| 英文摘要: |
| As we all know, Vitamin D deficiency may lead to osteoporosis and muscle weakness, increasing the risk for
osteoporotic fractures. the vitamin D level is directly related to juvenile rickets and osteoporosis in the elderly. However, a large number
of epidemiological evidence show that lack of vitaminD (VD) is an important risk factors for a variety of diseases, including cancer,
cardiovascular disease, depression, Alzheimer's disease, infectious disease, musculoskeletal function decline, etc. In contrast, vitamin D
supplementation can reduce the risk of many diseases, a lot of patients with disease were beneficial from VD. In this study, we reviewed
the existing research findings on the association between vitamin D levels and a variety of clinical disease, and consider the concentration
of human serumVitamin D monitoring and clinical significance. |
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