| 谢渡江 周陵 李小波 张幼祥 王蓉 陈绍良.国产Amplatzer蘑菇伞介入治疗中老年动脉导管未闭的近中期疗效分析[J].现代生物医学进展英文版,2014,14(19):3703-3705. |
| 国产Amplatzer蘑菇伞介入治疗中老年动脉导管未闭的近中期疗效分析 |
| The Short and Intermediate TermEfficacy of Transcatheter Closureby Homemade Amplatzer MushroomOccluderof Patent Ductus Arteriosus for the Middle-aged or Geratic Patients |
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| DOI： |
| 中文关键词: 动脉导管未闭 介入治疗 中老年 近中期疗效 国产封堵器 |
| 英文关键词: Patent ductus arteriosus Interventional therapy Middle-aged patients Short and intermediate term efficacy Homemade
occluder |
| 基金项目: |
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| 中文摘要: |
| 目的：评价国产Amplatzer蘑菇伞介入治疗中老年动脉导管未闭(patent ductus arteriosus，PDA)的近中期临床疗效及安全性。
方法：选择2007 年1 月至2011 年12 月我院收治的32 例中老年PDA患者，经临床、心电图、X 线及经胸超声心动图(TTE)检查确
诊，均成功行介入治疗。术后行心电图、X线胸片、TTE 随访。结果：32例均1 次封堵成功，成功率100%。无重要并发症发生。随
访X线胸片显示肺血较术前减少，心胸比率不同程度缩小。术后48 小时(32 例)超声心动图显示左房内径(LAD)、左室舒张末内径
(LVDd)及肺动脉收缩压(PASP)较封堵前明显缩小(P<0.01)；术后1、3、6 月(32 例)超声心动图随访显示LAD 及LVDd、PASP 进一
步缩小；术后1 年（30 例)、术后2年（20 例)、术后3 年（12 例)、术后4 年（5 例)超声心动图随访显示心脏大小及肺动脉收缩压恢复
正常。结论：国产Amplatzer蘑菇伞介入治疗中老年PDA 具有操作简单、创伤小、安全且技术成功率高、住院时间短等优点，近中
期疗效明确，并发症少。 |
| 英文摘要: |
| Objective:To evaluate the short and intermediate term efficacy as well as safety of transcatheter closure by homemade
Amplatzer mushroom occluder of patent ductus arteriosus in the treatment of middle-aged or geratic patients.Methods:32 cases with
PDA who were confirmed by clinical manifestation, electrocardiogram (ECG), X-ray fluoroscopy, transthoracic color Doppler
echocardiography (TTE) from January 2007 to December 2011 were selected and received the transcatheter occlusion. Then the
follow-ups were conducted.Results:32 cases were all successfully occluded with the rate of 100%. In follow-ups, X-ray fluoroscopy
showed pulmonary venous pleonaemia reduced and cardio-thoracic ration decreased. After 48 hours, the LAD, LVDd and PASP reduced
obviously (P<0.01); after 1 year (30 cases), 2 years (20 cases), 3 years (12 cases) and 4 years (5 cases). There was no death, complication
or therapy.Conclusion:Transcatheter closure of PDA in middle-aged or geratic patients using the homemade Amplatzer mushroom
occluder was safety and efficacy with easy procedure, less complication, high successful rate and shorter hospitalization. |
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