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目的：系统评价呼吸道过敏性疾病和社会心理因素的关系。方法：计算机检索Cochrance 图书馆、Medline、EMbase、Pubmed、 CBM、CNKI等数据库，查找包括心理社会因素对呼吸道过敏性疾病的影响或者呼吸道过敏性疾病对精神健康影响的临床研究，根据纳入和排除标准选择文献，对符合纳入标准的文献进行Meta 分析，计算其合并OR值及95%CI。结果：共纳入20 个病例研究(13 篇文献),其中13 个研究评估心理社会因素对呼吸道过敏性疾病的影响，7 个研究评估效果呼吸道过敏性疾病对心理健康的影响。在这些研究中呼吸道过敏性疾病是评估哮喘和过敏性鼻炎。Meta 分析结果显示社会心理因素和呼吸道疾病的发生发展有关[OR=1.77，95%CI（1.42,2.22）]，呼吸道过敏性疾病与未来不健康的心理发生发展有关[OR= 1.73，95%CI（1.47,2.03）]。结论：当前的研究发现呼吸道过敏性疾病和社会心理因素有很大的关系。这支持在呼吸道过敏性疾病治疗除了传统的生理和药理干预外，心理干预呼吸道对过敏性疾病的预防和管理也发挥作用。

英文摘要:

Objective:To investigate the relationship systematically between psychosocial factors and respiratory atopic disorders.Methods:Medline, PsycINFO, Web of Science, and PubMed were searched. The studies included prospective cohort studies investigating the influence of psychosocial factors on respiratory atopic disorders and the effect of respiratory atopic disorders on mental health.Results:There were 20 studies (in 13 articles), of which 13 evaluated the effect of psychosocial factors on respiratory atopic disorders and 7 evaluated the effect of respiratory atopic disorders on mental health. The major respiratory atopic disorders assessed in these studies was asthma and allergic rhinitis. The overall meta-analysis exhibited a positive association between psychosocial factors and future respiratory atopic disorder [OR=1.77,95%CI (1.42，2.22)] as well as between respiratory atopic disorders and future poor mental health [OR=1.76,95%CI (1.48，2.08)].Conclusion:The current review revealed a robust relationship between psychosocial factors and respiratory atopic disorders. This supports the use of psychological in addition to conventional physical and pharmacological interventions, in the successful prevention and management of respiratory atopic disorders.

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