| 李陆 阎嘉 刘佳 刘玉晶 贾慧芳.凝血因子及血浆蛋白类制品的研究现状及发展前景[J].现代生物医学进展英文版,2014,14(18):3578-3580. |
| 凝血因子及血浆蛋白类制品的研究现状及发展前景 |
| The Research Status and Prospects of Coagulation Factors and PlasmaProtein Products |
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| DOI： |
| 中文关键词: 血浆制品 凝血因子 血浆蛋白 白蛋白 免疫球蛋白 |
| 英文关键词: Blood biological Coagulation factors Plasma protein Albumin Immunoglobulin |
| 基金项目: |
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| 中文摘要: |
| 血浆制品主要是以血浆为原料，经特殊的分离提纯而得到的血浆单一组分，也有部分血浆制品可以通过生物工程技术合
成。不同的组分具有相应的功能，血浆制品是一种特殊的药品。目前市场上分离且临床上使用的血浆制品主要有凝血因子、白蛋
白、免疫球蛋白以及凝血酶、蛋白C、琢1- 抗胰蛋白酶、alpha2- 巨球蛋白、组织纤溶酶原激活剂、补体脂酶抑制剂、血清胆碱酯酶、铜蓝
蛋白、转铁蛋白、纤维结合蛋白\ 高密度脂蛋白等微量血浆蛋白等。凝血因子根据不同的功能分为FI、FII、FIII、FIV、FV、FVII、
FVIII、FIX、FX、FXI、FXII以及因子FXIII。随着技术的发展已经人们对血浆制品的认知度越来越高，血浆制品正已前所未有的速
度发展。 |
| 英文摘要: |
| The mainly raw material for plasma products is plasma, then the components are obtained by special separation and
purification. Some of plasma products can also be synthesized by biological engineering technology. Every component has corresponding
function, and plasma products are a special kind of drugs. Clinical using of blood products in the market are including coagulation
factors, albumin, immunoglobulin, and thrombin, protein C, 琢1-anti-trypsin, alpha2-macroglobulin, tissue plasminogen activator,
complement lipase inhibitor, serum cholinesterase, ceruloplasminthe micro plasma protein of the protein, transferrin, fibronectin,
high-density lipoprotein and so on, The coagulation factors were divided into FI, FII, FIII, FIV, FV, FVII, FVIII, FIX, FX, FXI, FXII and
factor FXIII depending on the function. The plasma products developing are unprecedented with the increasing awareness of plasma
products. |
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