| 魏占云苏文娟张艳红马丽娜韩蕊.老年原发性高血压患者血压晨峰与早期肾损害的临床观察[J].现代生物医学进展英文版,2014,14(15):2886-2888. |
| 老年原发性高血压患者血压晨峰与早期肾损害的临床观察 |
| Clinical Observation on the elderly hypertensive patients with morning bloodpressure peak and early renal damage |
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| DOI： |
| 中文关键词: 老年 原发性高血压 血压晨峰 肾功能损害 |
| 英文关键词: Elderly Hypertension Morning blood pressure surge Renal dysfunction |
| 基金项目:首都医科大学宣武医院综合科北京100053 |
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| 中文摘要: |
| 摘要目的：探讨老年原发性高血压患者血压晨峰与早期肾损害的关系。方法：选择我院收治的94 例老年原发性高血压患者进行
24 小时动态血压监测，并根据监测结果，将患者分为晨峰组62 例和非晨峰组32 例，检测和比较两组的血肌酐和尿素氮、12 小时
尿微量蛋白、尿茁2 微球蛋白、空腹血糖、血脂等指标。结果：老年高血压患者晨峰组12 小时尿微量蛋白、尿茁2 微球蛋白均显著高
于非晨峰组(P＜0.05)；晨峰血压与12 小时尿微量白蛋白(r=0.374)、尿茁2 微球蛋白(r=0.456)呈显著正相关。结论：老年原发性高血
压患者血压晨峰与早期肾损害有关，治疗高血压的同时重视控制晨峰血压有重要意义。 |
| 英文摘要: |
| ABSTRACT Objective:To investigate the relationship between blood pressure morning peak and early kidney damage of elderly
hypertensive patients.Methods: 94 elderly patients with essential hypertension were selected and 24-hour ambulatory blood pressure
monitoring were detected. According to monitoring results, the patients were divided into morning peak group (62 cases) and non-MBPS
group (32 cases), the serum creatinine and blood urea nitrogen, 12-hour urine protein, urine beta 2-microglobulin, fasting blood glucose,
blood lipids and other indicators of detection were tested and compared between two groups. Results:The 12-hour urine protein, urinary
beta2-microglobulin of morning peak group were both significantly higher than those of the non-MBPS group (P<0.05); morning peak
blood pressure and 12-hour urinary albumin (r=0.374), urinary beta2-microglobulin (r=0.456) showed a significant positive correlation.
Conclusion:The morning blood pressure peak of elderly patients with essential hypertension was correlated with early renal injury, morning
peak blood pressure control was also important as the treatment of hypertension. |
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