| 徐东伟 薛峰 张建军 夏强.肝细胞癌复发转移机制的研究进展[J].现代生物医学进展英文版,2014,14(14):2786-2789. |
| 肝细胞癌复发转移机制的研究进展 |
| Progress in Mechanisms of Recurrence and Metastasisof Hepatocellular Carcinoma |
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| DOI： |
| 中文关键词: 肝细胞癌 复发转移 机制 |
| 英文关键词: Hepatocellular carcinoma Recurrence and metastasis Mechanism |
| 基金项目: |
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| 中文摘要: |
| 复发转移是影响肝细胞癌患者治疗疗效和长期生存的最主要因素，探讨肝细胞癌复发转移的机制，寻找早期诊断复发转移、
判断患者预后的生物标记和干预治疗的靶点，已成为当今肝细胞癌研究的热点与难点。本文就其复发转移部分机制如microRNA、CD147 分
子、肿瘤干细胞以及肿瘤微环境等几方面的研究进展进行综述。 |
| 英文摘要: |
| Recurrence and metastasis are the most important factors which affect the prognosis and the survival rate of the
patients suffering fromhepatocellular carcinoma. Studies of hepatocellular carcinoma focus on investigating the mechanism of recurrence
and metastasis and seeking biological markers for early diagnosis and prediction of prognosis and targets for interfering therapy are the
hot and difficult spot at present. This review is mainly focused on the research progression in fields such as microRNA,CD147,cancer
stemcells and tumor microenvironment. |
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