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目的：研究青天葵水提取液、醇提取液和水醇提取液对金黄色葡萄球菌、大肠杆菌、白色念珠菌、伤寒沙门菌、绿脓杆菌、黑曲霉菌6 种菌株的抑菌效果。方法：制备青天葵3 种提取液，采用试管两倍稀释法测定3种提取液对金黄色葡萄球菌等6 种菌株的最低抑菌浓度（MIC）。结果：青天葵水提取液对伤寒沙门菌的抑菌作用较强（MIC 为12.5%），对金黄色葡萄球菌、大肠杆菌、绿脓杆菌和黑曲霉菌的抑菌作用较弱（MIC 为50%）；醇提取液对伤寒沙门菌和绿脓杆菌都有很强的抑菌作用（MIC 为6.25%），对金黄色葡萄球菌也有较强的抑菌活性（MIC 为12.5%），对大肠杆菌的抑菌作用较弱（MIC 为50%）；水醇提取液的抑菌活性与醇提取液相当。结论：青天葵对金黄色葡萄球菌等6 种菌株表现出不同程度的抑制活性。

英文摘要:

Objective:To study The inhibitory effect of Folium Nerviliae water extract, Alcohol extract, Hydroalcoholic extract to the 6 kinds of bacterial: Staphylococcus aureus, escherichia coli, staphylococcus aureus, salmonella typhosa, pseudomonas aeruginosa and aspergillus niger.Methods:Three kinds of FoliumNerviliae extract were prepared, two times dilution method was used for determinating MIC of three kinds of extract to 6 kinds of bacterial.Results:FoliumNerviliae Water extract showed strong antibacterial activity to salmonella typhosa （MIC was 12.5%），showed weak antibacterial activity to staphylococcus aureus, escherichia coli, pseudomonas aeruginosa and aspergillus niger （MIC was 50%）, alcohol extract showed strong antibacterial activity to salmonella typhosa and pseudomonas aeruginosa （MIC was 6.25%）, showed relative strong antibacterial activity to staphylococcus aureus （MIC was 12.5%）, showed weak antibacterial activity to escherichia coli （MIC was 50%）, water-alcohol extract's antibacterial activity was similar to alcohol extract.Conclusion:FoliumNerviliae shows different degrees of inhibitory activity to 6 strins.

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