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目的：乳腺癌是我国女性最常见的恶性肿瘤。生命质量作为一种新的医学综合评价技术，包括了对患者身体状况、心理、社会功能以及与疾病或治疗有关的症状等情况的全面评估，其在癌症患者疗效评估中的应用日益增多。乳腺癌患者生命质量调查量表QLICP-BR 具有中国文化特色、适合中国国情，具有较好的效度、信度和一定的反应度，适用于中国乳腺癌患者的生命质量测定。本研究旨在观察乳腺癌患者术后生命质量情况并评估各因素对其生命质量的影响，为进一步提高乳腺癌患者术后生命质量提供指导。方法：采用乳腺癌患者生命质量调查量表QLICP-BR收集资料，调查245 名住院治疗的乳腺癌患者术后一般情况及生命质量，并分析其影响因素。结果：乳腺癌患者术后生存质量总分为88.44 ± 12.32，其主要影响因素有患病年龄、居住环境、文化程度、家庭经济收入、工作状况、婚姻状况、治疗情况、术后时间及目前治疗情况等(P＜0.05)。其中年龄较长、居住城镇、文化水平较高、收入较高、在职、已婚、手术治疗联合化疗、术后时间较长以及当前正予以放疗的患者的生存质量评分较高。结论：乳腺癌患者术后生命质量为一般水平，多项因素对其有显著影响。临床上应针对主要影响因素制定综合有效的干预措施，提高乳腺癌患者术后的生命质量。

英文摘要:

Objective:Breast cancer is the most common malignancy of women in China. Quality of life (QOL) including assessment of physical condition, psychological condition, social functions and disease-related symptoms or treatment-related symptoms of patients is nowadays one of the most important outcome measures in cancer researches because it can fully reflect the overall situation of patients after surgical treatment. QLICP-BR Scale with Chinese cultural characteristics, is suitable for cancer patients in China. It is of good validity, reliability and responsivness, and can be uesed to assess QOL for Chinese breast cancer patients. Accordingly, our investigation was performed to evaluate the QOL of breast cancer patients after surgical treatment and its influencing factors with the purpose of providing further advice to improve QOL of these patients.Methods:A survey with Quality of Life Instruments for Cancer Patients-Breast Cancer (QLICP-BR) was undertaken in 245 breast cancer patients who had got operation in our hospital. Simultaneously, with the results of QLICP-BR, we conducted statistical analysis to evaluate the possible factors influencing the QOL of breast cancer patients.Results:The total standardized score of QLICP-BR was 88.44± 12.32 and statistical analysis indicated that QOL standardized scores were significantly influenced by different age, birth place (metropolis or rural), degree of education, domestic income, occupation, marital status, treatment, postoperative time and current treatment (P<0.05). In brief, the older, the urban, the educated, the high-income, the occupied and the married ones got higher scores in our investigation. In addition, the patients those got surgery and chemotherapy treatment or had long duration after operation or underwent radiotherapy currently got an improved QOL.Conclusion:The QOL of breast cancer patients was at the general level. A number of factors have significant impacts on it. Those influencing factors may be of use to help make comprehensive and effective interventions to improve QOL of breast cancer patients.

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