| 王淑琴 段霄燕 任晓兰 欧立 刘兴德 邹秋富 陈娟.原发性高血压合并冠心病患者血清CRP的变化[J].现代生物医学进展英文版,2014,14(13):2504-2506. |
| 原发性高血压合并冠心病患者血清CRP的变化 |
| Changes and clinic significance of serumC-reactive protein in patients withcoronary artery disease and hypertension |
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| DOI： |
| 中文关键词: C- 反应蛋白 原发性高血压 冠心病 炎症 冠状血管造影术 |
| 英文关键词: C-reactive protein Hypertension Coronary artery disease Inflammation Coronary angiography |
| 基金项目:贵阳市科学技术计划项目((2006)筑科农字27-5）；贵州省卫生厅科学技术基金项目(（
2006)130-6） |
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| 中文摘要: |
| 目的：探讨原发性高血压合并不同类型冠心病患者血清C- 反应蛋白(CRP)的变化及其意义。方法：用全自动生化分析仪检
测71 例原发性高血压患者和28例健康对照组人群的血清CRP 水平，所有研究对象均行选择性冠状动脉造影检查。将原发性高
血压组病人根据冠脉造影检查分为单纯原发性高血压组(EH)，原发性高血压合并稳定性心绞痛组(EH+SAP)、原发性高血压合并
不稳定心绞痛组(EH+UAP)、原发性高血压合并心肌梗死组(EH+MI)，比较各组患者血清CRP 水平的差异。结果：①与对照组比
较，EH 组及EH合并CAD 各组患者血清CRP 均显著升高(P<0.05)；②与EH 组比较，EH+UAP 和EH+MI 组血清CRP水平均显
著升高(P<0.01)；③与EH+SAP组比较，EH+AMI组和EH+UAP 组血清CRP水平均显著升高(P<0.01)。结论：冠心病合并原发性
高血压患者血CRP 水平与冠状动脉病变程度与斑块稳定程度存在正相关性。 |
| 英文摘要: |
| Objective:To study the changes and clinic significance of Serum C-reactive protein (CRP) in patients with coronary
heart disease (CAD) and hypertension (EH).Methods:CRP levels of 71 patients with hypertension (EH) was diagnosed by coronary
angiography, and 28 persons without the disease (control group) were measured with automatic biochemical analysator. All the EH
patients were divided into sub-groups of hypertension (EH), hypertension with stable angina pectoris (EH+SAP), hypertension with
unstable angina pectoris(EH+UAP) and hypertension with acute myocardial infarction(EH+AMI). All patients and control group people
were operated coronary angiography.Results:① Compared with that of control group, CRP in patients with EH significantly higher than
that of control group (P<0.05); ② Compared with that of control group, CRP in patients with EH+SAP, EH+UAP and EH+AMI
sinnificantly higher than that of control group (P<0.05); ③ Compared with that of EH group, CRP in patients with EH+UAP and
EH+AMI were significantly higher (P<0.01), also, compared with that of patients with EH+SAP, CRP in patients with EH+UAP and
EH+AMI were markedly higher (P<0.01).Conclusion:There is positive correlation between level of CRP in patients with coronary artery
disease and hypertension. |
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