| 李元曦 曲学华 李洪颖 罗振红 丛珊 刘冰 崔晓光.右美托咪定与咪达唑仑用于肠镜检查患者镇静效果比较[J].现代生物医学进展英文版,2014,14(12):2293-2295. |
| 右美托咪定与咪达唑仑用于肠镜检查患者镇静效果比较 |
| The Comparison of Sedation with Dexmedetomidine and Midazolam Usedfor Enteroscopy |
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| DOI： |
| 中文关键词: 肠镜 右美托咪定 咪达唑仑 镇静效果 |
| 英文关键词: Colonoscopy Dexmedetomidine Midazolam Sedation |
| 基金项目:黑龙江省自然科学基金重点项目（ZD201017) |
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| 中文摘要: |
| 目的：比较右美托咪定与咪达唑仑用于肠镜检查患者效果比较。方法：肠镜检查的患者60 例，随机分为两组：D 组静脉输注
右美托咪定0.6 滋g/kg，M组静脉输注咪达唑仑0.08 mg/kg，均用生理盐水10 mL稀释，10 min 输注完毕后进行肠镜检查。观察患
者血流动力学指标及呼吸指标的变化，是否完成肠镜，患者的满意度以及检查过程中的不良反应。结果：右美托咪定组所有患者
镇静满意，均能很好耐受肠镜检查，并且检查过程中MAP、HR和SpO2稳定（P>0.05）。咪达唑仑组镇静时有轻度呼吸抑制，肠镜检
查过程中MAP 和HR升高（P<0.05），插管耐受率低于右美托咪定组（P<0.05）。结论：右美托咪定用于肠镜镇静有效，无呼吸抑制，
血流动力学稳定，是理想的辅助药。 |
| 英文摘要: |
| Objective:Dexmedetomidine compared with midazolam given for colonoscopy patient Comparison.Methods:60 patients
with Colonoscopy were randomly divided into two groups. Group D was given dexmedetomi- dine with dose of 0.6 滋g/kg, while
groupMreceived intravenous infusion of midazolam0.08mg/kg, both were diluted with saline 10 mL. 10min after infusion, patients were
underbent colonoscopy. hemodynamic and respiratory indicators of change, whether complete colonoscopy, patient satisfaction, and adverse
reactions during the inspection were observed.Results:dexmedetomidine sedation in all patients given group were well tolerated
with colonoscopy process of MAP, HR and SpO2 stable (P>0.05). Midazolam group had mild res- piratory depression and sedation, and
MAP and HR during colonoscopy is below tolerance compared with dexmedetomidine group (P<0.05).Conclusion:Dexmedetomidine,
with less respiratory depression and hemodynamic stability, is the ideal adjuvant drugs for colonoscopy sedation. |
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