欢迎访问《现代生物医学进展》编辑部！

目的：自身免疫性肝病的发病机理至今尚未明确，与多种疾病之间存在着联系，临床诊断具有一定的难度。本研究利用超声弹性成像技术定量分析自身免疫性肝病的病理特征，探讨该技术的诊断价值，为自身免疫性疾病的治疗提供诊断依据。方法：选取我院2011 年3 月-2013 年6 月收治的自身免疫性肝病患者182 例，随机分为观察组和对照组。观察组98 例患者采用弹性成像定量分析的方法进行诊断，对照组84 例则采用常规病理学诊断。观察并比较两组患者的诊断准确率及诊断耗时。结果：观察组检出94 例，诊断率为95.92%；对照组检出81 例，诊断率为96.43%，两组诊断准确率比较无明显差异(P>0.05)。观察组平均诊断耗时为5.6 h；对照组平均诊断耗时为11.6 h，观察组诊断时间比对照组短，差异具有统计学意义(P<0.05)。结论：弹性成像定量分析对自身免疫性肝病的诊断准确率与病理活检诊断具有较好的一致性，且诊断耗时短、患者依从性好，值得在临床中进一步推广应用以辅助病理诊断，避免误诊或漏诊现象发生。

英文摘要:

Objective:It is difficult to make sure of the pathogenesis of the autoimmune liver diseases which is associated with several factors. This article aims to exploring the diagnostic values of quantitative elasticity imaging on the autoimmune liver diseases by analyzing the pathological characteristics of AILD so as to provide a reference for clinical treatment.Methods:182 patients with the autoimmune liver disease who were treated in our hospital from March 2011 to June 2013 were selected and randomly divided into the observation group and the control group. Ninety-eight cases in the observation group were inspected by the quantitative elasticity imaging, while another eighty-four cases in the control group were diagnosed by the pathology. Then the accuracy and time of diagnosis were recorded and compared between two groups. Results: The accuracy of the diagnosis was 95.92% in the observation group which was similar to the 96.43%in the control group with no significant difference(P>0.05). The average time for the diagnosis was 5.6 hours in the observation group which was shorter than 11.6 hours in the control group with statistically significant difference (P<0.05).Conclusion:It is indicated that the quantitative elasticity imaging should be well promoted and make contribution to the pathological diagnosis of autoimmune liver disease with the advantages of high consistency in accuracy and shorter time.

View Full Text View/Add Comment Download reader