| 朱淑萍1 丁久韦2 刘碧华3 冯立明4 刘冰4 曲学华4 蒲江北3△.雷米芬太尼联合丙泊酚对妇科腹腔镜手术患者的血流动力学
及麻醉苏醒的影响[J].现代生物医学进展英文版,2014,14(10):1942-1945. |
| 雷米芬太尼联合丙泊酚对妇科腹腔镜手术患者的血流动力学
及麻醉苏醒的影响 |
| Influence of Hemodynamics and Anesthesia Emergencefrom Remifentanil Combined with Propofol Anesthesiain Patients Undergoing Gynecological Laparoscopy |
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| DOI： |
| 中文关键词: 妇科腹腔镜手术 雷米芬太尼 丙泊酚 |
| 英文关键词: Gynecological laparoscopy Remifentanil Fentanyl |
| 基金项目: |
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| 中文摘要: |
| 摘要目的：探讨雷米芬太尼联合丙泊酚对妇科腹腔镜手术患者的血流动力学及麻醉苏醒的影响。方法：将116例拟行妇科腹腔
镜手术患者随机分为观察组和对照组，观察组给予雷米芬太尼联合丙泊酚全凭静脉麻醉，对照组给予芬太尼联合丙泊酚全凭静
脉麻醉。比较两组术中平均动脉压(MAP)、心率（HR）、血气分析指标、患者麻醉后睁眼时间、拔管时间及答问切题时间。结果：麻醉
诱导后两组平均动脉压(MAP)及心率（HR）均显著下降(P<0.05)；观察组插管即刻及插管后2 min MAP 及HR 显著低于对照组
（P<0.05）；观察组麻醉后睁眼时间、拔管时间、答问切题时间显著早于对照组（P<0.05）；与气腹前相比，气腹10 min、20 min 及60
min 的PaCO2均升高(P<0.05)，两组各时点其他血气分析指标比较无显著差别(P>0.05)。结论：妇科腹腔镜手术给予雷米芬太尼联
合丙泊酚全凭静脉麻醉，可显著减轻插管应激心血管反应，保持血流动力学稳定，效果优于芬太尼联合丙泊酚麻醉。 |
| 英文摘要: |
| ABSTRACT Objective:To explore the anesthetic effect of remifentanil combined with propofol anesthesia in gynecological laparoscopy.
Methods:116 cases scheduled for laparoscopic surgery were randomly divided into control group and experience group. Experience
group received total intravenous anesthesia of remifentanil-propofol. Control group were given fentanyl-propofol total intravenous
anesthesia. The change of mean arterial pressure (MAP), heart rate (HR) and blood gas analysis indexes during operation were compared
in two groups. Duration of opening eyes on verbal command, extubation time and the recovery time of awareness were recorded.
Results:Blood pressure and heart rate of two groups after anaesthetic induction greatly decreased (P<0.05); MAP and HR on endotracheal
intubation instanter and 2 minutes after intubation in experience group were much lower than that in control group (P<0.05); Duration of
opening eyes on verbal command, extubation time and the recovery time of awareness in experience group were much shorter than that in
control group (P<0.05); Compared with before pneumoperitoneum, PaCO2 greatly increased on 10 min, 20 min and 60 min after
pneumoperitoneum (P<0.05); There were no significant difference of blood gas analysis indexes between two groups (P>0.05).
Conclusion:Remifentanil combined with anesthesia for patients undergoing gynecological laparoscopy can greatly decrease intubation
stress response and maintain hemodynamics stable. The effect of remifentanil combined with propofol anesthesia was superior to
fentanyl-propofol in gynecological laparoscopy. |
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