| 宋爱玲卜丽娜△ 贾卫红韩燕燕杨栋才温鸿请.肺通气功能程度与慢性阻塞性肺疾病患者夜间低氧发生
的相关性分析*[J].现代生物医学进展英文版,2014,14(10):1911-1913. |
| 肺通气功能程度与慢性阻塞性肺疾病患者夜间低氧发生
的相关性分析* |
| Correlation Between the Degree of Pulmonary Ventilation Functionand Nocturnal Hypoxia Occursin Patients WithchronicObstructive Pulmonary Disease* |
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| DOI： |
| 中文关键词: 肺通气功能 夜间低氧 慢性阻塞性肺疾病 |
| 英文关键词: Pulmonary ventilation function Nocturnal hypoxia Chronic obstructive pulmonary disease |
| 基金项目:西安市卫生局科研项目（2012004） |
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| 中文摘要: |
| 摘要目的：研究肺通气功能程度与慢性阻塞性肺疾病患者夜间低氧发生的相关性。方法：选取2012 年1 月至2013 年6 月我院
治疗的60 例稳定期慢性阻塞性肺疾病患者，按肺通气功能分为轻度、中度、重度、极重度4 组，每组15 例，监测记录研究对象肺
通气功能指标及夜间血氧指标，比较各组监测指标的差异，并分析其相关性。结果：不同病情程度COPD 患者FEV1/FVC、FEV1、
FVC、PEF、RV、RV/TLC、MsaO2、ODI、WsaO2、LsaO2、SIT90%有差异（P<0.05）；极重度和重度比较FEV1/FVC、FEV1、RV、MsaO2、ODI
、WsaO2、LsaO2、SIT90%有差异（P<0.05）；极重度和中度比较FEV1/FVC、FEV1、FVC、PEF、RV、RV/TLC、MsaO2、ODI、WsaO2、
LsaO2、SIT90%有差异（P<0.05）；极重度和轻度比较FEV1/FVC、FEV1、FVC、PEF、RV、RV/TLC、MsaO2、ODI、WsaO2、LsaO2、
SIT90%有差异（P<0.05）；重度和中度比较FEV1/FVC、FEV1、FVC、PEF、RV/TLC、MsaO2有差异（P<0.05）；重度和轻度比较
FEV1/FVC、FEV1、FVC、PEF、RV/TLC、MsaO2、ODI、LsaO2有差异（P<0.05）；中度和轻度比较FEV1/FVC、FEV1、FVC、PEF、ODI有
差异（P<0.05）。COPD患者的肺通气功能FEV1 与MsaO2呈正相关(r=0.683，P＜0.05）。结论：肺通气功能程度与慢性阻塞性肺疾
病患者夜间低氧发生具有相关性。 |
| 英文摘要: |
| ABSTRACT Objective：To study thecorrelation between the degree of pulmonary ventilation function and nocturnal hypoxia occurs
in patients with chronic obstructive pulmonary disease.Methods： Selected 60 patients with stable chronic obstructive pulmonary diseasefrom
January 2012 to June 2013 in our hospital, divided into mild, moderate, severe , very severe four groups by pulmonary function, 15
cases in each group, monitoring records studied pulmonary function indicators and nocturnal oxygen index , comparing the differences of
indicators in each group , and analyze their relevance.Results： Among four groups COPD FEV1/FVC, FEV1, FVC, PEF, RV, RV / TLC,
MsaO2, ODI, WsaO2, LsaO2, SIT90% had differences (P<0.05);compared very severe and severe group FEV1/FVC, FEV1, RV, MsaO2,
ODI, WsaO2, LsaO2, SIT90% had differences (P<0.05); compared very severe and moderate group FEV1/FVC, FEV1, FVC, PEF, RV,
RV / TLC, MsaO2, ODI, WsaO2, LsaO2, SIT90% had differences (P<0.05);compared very severe and mild group FEV1/FVC, FEV1,
FVC, PEF, RV, RV / TLC, MsaO2, ODI, WsaO2, LsaO2, SIT90%had differences (P<0.05 ) ; compared severe and moderate group FEV1/
FVC, FEV1, FVC, PEF, RV / TLC, MsaO2 had differences (P<0.05); compared severe and mild group FEV1/FVC, FEV1, FVC, PEF, RV
/ TLC, MsaO2, ODI, LsaO2 had differences (P<0.05); compared moderate and mild group FEV1/FVC, FEV1, FVC, PEF, ODI had differences
(P<0.05). Pulmonary function in patients with COPD MsaO2 was positively correlated with FEV1 (r = 0.783, P<0.05).
Conclusion：pulmonary ventilation function correlated with the degree of chronic obstructive pulmonary disease in patients with nocturnal hypoxia. |
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