| 周海华 杨倞 孙永健 孟岩 霍爽.肝门部胆管癌临床诊断与放疗疗效分析[J].现代生物医学进展英文版,2014,14(9):1665-1667. |
| 肝门部胆管癌临床诊断与放疗疗效分析 |
| Diagnosis and Effects of the Radiotherapy on HilarCholangiocarcinoma |
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| DOI： |
| 中文关键词: 胆管肿瘤 根治性手术 姑息治疗 放射治疗 临床效果 |
| 英文关键词: Bileduct neoplasms (Non)radical surgery Clinical diagnosis Treat analysis |
| 基金项目:国家自然科学基金项目（81170397） |
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| 中文摘要: |
| 目的：探讨不同手术方式治疗肝门部胆管癌的效果及其对术后放疗的影响。方法：回顾性分析我科自2008 年6 月至2012
年6 月间收治的60 例肝门部胆管癌患者的临床资料，根据手术方式不同，将所选病例分为两组，其中26 例接受根治性切除术，
34例患者采用姑息性手术进行治疗。对比不同手术方式下放疗后患者生存情况。结果：围手术期死亡1 例。两组患者各有2 例患
者失访。随访的23 例根治手术患者1、3、5 年间的生存率为19(82.6%)、10(43.5%)、2(8.7%)；32 例姑息性手术患者1、3、5 年间的生
存率为15(46.9%)、4(12.4%)、0(0%)。根治性手术后患者1、3、5年间的生存率显著性高于姑息性手术治疗的患者，差异具有统计学
意义(P<0.05)。结论：通过术前影像学诊断，选择合理的手术方式，联合术后放疗，可有效延长肝门部胆管癌患者的生存时间。 |
| 英文摘要: |
| Objective:To investigate the clinical effects of different operation methods combined with the radiotherapy on the
treatment of hilar cholangiocarcinoma.Methods:A retrospective analysis was conducted about 60 cases with hilar cholangiocarcinoma
who were treated in our hospital from June 2008 to June 2012.Results:The rate of misdiagnosis was high without specific symptoms in
the early stage. There was one died when undergoing the radical surgery, and two cases were missed the follow-up in each group. The
median survival time of 23 patients treated by radical resection was 30 months with the 1, 3, 5-year survival rate 19(82.6%), 0(43.5%), 2
(8.7%) respectively. While the median survival time of the non-radical 32 patients was 16 months with the 1, 3, 5-year survival rate 15
(46.9%), 4 (12.4%), 0 (0%) respectively.Conclusions:It is indicated that a reasonable surgical approach combined with postoperative
radiotherapy should be performed by the preoperative imaging diagnosis in order to effectively extend the hilar survival time of patients. |
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