| 郭静池艳春△ 陈曦李洪波张堃.低钙透析液联合醋酸钙对血液透析患者高磷血症的影响[J].现代生物医学进展英文版,2014,14(8):1522-1524. |
| 低钙透析液联合醋酸钙对血液透析患者高磷血症的影响 |
| Influence f low CalciumDialysate Combined with CalciumAcetate onHyperphosphatemia of Patients with Hemodialysis |
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| DOI： |
| 中文关键词: 低钙透析液 醋酸钙 高磷血症 血液透析 |
| 英文关键词: Low calciumdialysate Calciumacetate Hyperphosphatemia Hemodialysis |
| 基金项目: |
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| 中文摘要: |
| 摘要目的：研究低钙透析液联合醋酸钙治疗对血液透析患者血磷、血钙及甲状旁腺激素iPTH水平的影响。方法：将30例维持性
血液透析患者随机分为试验组和对照组，在试验期间所有患者均低磷饮食，两组透析液钙浓度均为1.25 mmol/L，试验组同时给予
醋酸钙治疗，对照组不应用醋酸钙治疗，三个月后观察和比较两组患者的血钙、血磷及血iPTH水平的变化。结果：治疗前，两组各
组血磷、血钙、血磷和血iPTH 的水平比较差异均无统计学意义（P>0.05）。治疗后，对照组血钙水平明显下降(P<0.05)，血iPTH水
平略上升但无统计学意义(P>0.05)，血磷水平无显著变化（P>0.05）；试验组血iPTH 水平略下降(P>0.05)，血钙水平无明显变化
（P>0.05），但血磷明显下降(P<0.05)；且试验组血磷水平较对照组明显下降(P<0.05)，血钙水平显著高于对照组(P<0.05)，但在正常
范围内，两组血iPTH 水平比较无统计学意义(P>0.05)。结论：低钙透析液联合醋酸钙治疗可有效降低血液透析患者的血磷水平，
且不会导致高钙血症的发生。 |
| 英文摘要: |
| ABSTRACT Objective：To study the effect of low calcium dialysate combined with calcium acetate on serum phosphorus, calcium
and parathyroid hormone iPTH level of patients with hemodialysis. Methods：30 cases of maintenance hemodialysis patients were
randomly divided into the experimental group and control group. During the test, patients were supplemented with low phosphorus diet,
and dialysate calcium concentration of the two groups were 1.25 mmol/L. The experimental group was given calcium acetate for the
treatment at the same time. The control group did not use it, then the changes in serum calcium, phosphorus and parathyroid hormone
level of the two groups patients were observed and compared after three months. Results：Before treatment, no significant difference was
found in the serumcalcium, phosphorus and parathyroid hormone levels between the two groups(P>0.05). The serum calcium level of the
control group was decreased significantly (P<0.05), the serum iPTH level was slightly increased but had no statistical significance (P>0.
05), no chang was found in serumphosphorus level (P>0.05). The serumiPTH level of experimental group was slightly decreased (P>0.
05), no change was observed in serum calcium level (P>0.05), but the serum phosphorus decreased significantly (P<0.05); the serum
phosphorus level of experimental group was significantly lower than that of the control group (P<0.05), the serum calcium level was
significantly higher than that of the control group (P<0.05), but in the normal range, no statistical difference of serum iPTH level was
observed between the two groups (P>0.05).Conclusion： Low calcium dialysate combined with calcium acetate could efficiently reduce
the serumphosphate level of hemodialysis patients and hypercalcemia won't occur. |
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