| 王 琦
1
郭晓东
2△
孟繁平
2
李瑞生
2
张红萍.生长抑素联合奥美拉唑治疗重症胰腺炎的疗效分析[J].现代生物医学进展英文版,2014,14(6):1097-1100. |
| 生长抑素联合奥美拉唑治疗重症胰腺炎的疗效分析 |
| Effects of Somatostatin Combined with Omeprazole on the Treatment ofSevere Acute Pancreatitis |
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| DOI： |
| 中文关键词: SAP 生长抑素 有效率 奥美拉唑 |
| 英文关键词: SAP Somatostatin Clinical efficacy Omeprazole |
| 基金项目:国家自然科学基金青年科学基金项目( 30901795 ） |
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| 中文摘要: |
| 摘要 目的： 探讨重症胰腺炎患者采用生长抑素联合奥美拉唑治疗的临床效果。方法： 选取 2005 年 10 月至 2012 年 10 月医院收
治的老年重症胰腺炎患者 98 例。将所有患者随机分为观察组和对照组， 每组各 49 例，对照组患者采取常规方法治疗重症胰腺
炎， 观察组患者在此基础上加用生长抑素联合奥美拉唑进行治疗。两组患者的疗程均为 7 天， 治疗结束后，对两组患者的临床疗
效、 各项恢复指标和并发症等情况进行对比分析。结果： 观察组患者治疗的总有效率显著高于对照组(93.9% vs.71.4%， P<0.05)； 观
察组患者的平均住院、 肠道恢复、 腹痛腹胀缓解、 血淀粉酶、 尿淀粉酶等各项指标恢复至正常时间及预后均显著优于对照组， 差异
具有统计学意义(P<0.05)。结论： 采用生长抑素联合奥美拉唑治疗重症胰腺炎， 可以获得更高的疗效， 患者症状改善明显， 治疗时
间短， 并发症少， 死亡率低， 值得临床推广。 |
| 英文摘要: |
| ABSTRACT Objective：To explore the clinical effects of somatostatin combined with omeprazole on the treatment of severe acute
pancreatitis.Methods: 98 patients with severe acute pancreatitis who were treated in our hospital from October 2005 to 2012 were selected in our study and randomly divided into the observation group and the control group with 49 cases in each group. The patients in the
control group were treated by the conventional method, while the patients in the observation group were treated by somatostatin combined with omeprazole besides the conventional treatment. The course of the treatment was seven days. Then the clinical effect, recovery
time and incidence of complications of patients were compared and analyzed between two groups.Results: The treatment efficacy of patients in the observation group was 93.9% which was significantly higher than that of the patients in the control group 71.4% (P<0.05).
The average hospitalization, intestinal recovery, abdominal pain remission, AMY, UAMY and other indexes restored to normal time and
the prognosis of patients were significantly better than those of the patients in the control group, and there were statistically significant
differences between two groups(P<0.05).Conclusion: It is suggested that Elderly patients with severe pancreatitis treated by somatostatin
combined with omeprazole could be well promoted with the advantages of high effective rate, significant improvement of symptoms,
shorter time for treatment, less incidence of complications and lower death. |
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