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摘要目的：探讨PET/CT 和超声弹性成像(UE)在乳腺癌诊断中的价值。方法：回顾性分析2011 年1 月至2012 年5 月在我院确诊的173 例乳腺患者的临床资料，所有患者均行PET/CT 和UE 检查。依据病理组织活检和临床随访分别评价PET/CT 和UE 对乳腺癌诊断的灵敏性、特异性、准确性，并比较两者的结果。结果：PET/CT 和UE 诊断乳腺癌的灵敏性分别为98.8%和81.3%；特异性分别为84.3%和97.2%；准确性分别为90.7%和90.2%；两种方法联合检测诊断乳腺癌的灵敏性、特异性、准确性分别为98.8%、 98.1%、98.4%，UE 检测乳腺癌的敏感性明显低于PET/CT 及PET/CT+UE，PET/CT 检测乳腺癌的特异性明显低于UE 及 PET/CT+UE，PET/CT+UE 诊断乳腺癌的准确性显著提高(P<0.05)。结论：PET/CT 和超声弹性成像在乳腺癌诊断中均有较高的应用价值，各有优缺点，二者联合检测可提高乳腺癌诊断的准确率。

英文摘要:

ABSTRACT Objective:To investigate the clinical value of PET/CT and ultrasound elastography (UE) in the diagnosis of breast cancer. Methods:A retrospective analysis of 173 cases of breast cancer diagnosed from January 2011 to May 2012 was performed, all the patients underwent PET/CT and UE examination. The sensitivity, specificity and accuracy of PET/CT and UE in the diagnosis of breast cancer was analyzed according to the results of pathological tissue biopsy. Results:The sensitivity of PET/CT and UE were respectively 98.8%and 81.3%; the specificity of were respectively 84.3%and 97.2%; while the accuracy were respectively 90.7%and 90.2%; combination of the two methods, the sensitivity, specificity, and accuracy were respectively 98.8%, 98.1%, 98.4%。The sensitivity of UE was significantly lower than those of PET/CT and PET/CT+UE, the specificity of PET/CT was significantly lower than those of UE and PET/ CT+UE, while the accuracy of PET/CT+UE was significantly higher than those of PET/CT and UE (P<0.05).Conclusion: PET/CT and ultrasound elastography both possessed advantages and disadvantages in the diagnosis of breast cancer, the combination of which improved the accuracy of the diagnosis of breast cancer.

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