| 张晓莉 姚元庆 彭红梅 王黎娜 郭晓东 王辉.基础卵泡刺激素水平对IVF/ICSI-ET超排卵周期卵巢反应[J].现代生物医学进展英文版,2014,14(4):643-645. |
| 基础卵泡刺激素水平对IVF/ICSI-ET超排卵周期卵巢反应 |
| Prediction Values of bFSH on the Response to Ovaryin the IVF/ICSI-ET Super Ovulation Cycle |
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| DOI： |
| 中文关键词: 泡刺激素 体外受精 卵巢反应 促排卵 |
| 英文关键词: Follicle-stimulating hormone in vitro fertilization (ivf) Ovarian response Stimulated ovulation |
| 基金项目:国家自然科学基金青年科学基金项目(30901795) |
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| 中文摘要: |
| 目的：基础卵泡刺激素(bFSH)可以刺激精子生成和促进卵子成熟，是人体内重要的激素之一。本研究针对体外受精(IVF)周
期bFSH 水平的变化情况，探讨bFSH对卵巢反应的预测价值，为临床研究提供理论基础。方法：回顾性分析2012 年1 月-2012 年
12 月在我院生殖医学中心接受体外受精- 胚胎移植(IVF-ET)治疗的154例患者的临床资料，根据基础卵泡刺激素水平分为A 组
(bFSH≥10 IU/L)、B 组(8≤bFSH≤10 IU/L)和C 组(bFSH<8 IU/L)。对比分析三组对象的年龄、基础窦卵泡数(bAFC)、黄体生成素
(LH)含量、FSH/LH 值、促性腺激素(Gn)的用量、使用时间、受精率及临床妊娠率等。结果：三组患者的年龄、bAFC 及FSH/LH相比
较，差异具有统计学意义(P<0.05)；三组的Gn 用量和时间、获卵数及妊娠率比较，差异显著且具有统计学意义(P<0.05)；三组基础
LH 值及超排卵周期受精率无显著差异(P>0.05)。结论：基础卵泡刺激素(bFSH)对体外受精女性的卵巢储备功能具有一定的预测
价值，bFSH 水平的高低可作为预测女性不孕患者超排卵周期卵巢反应性的一项重要指标，值得临床推广和应用。 |
| 英文摘要: |
| Objective:The basic follicle-stimulating hormone(bFSH) is one of the most important hormones in human body which
could stimulate the production and maturity of sperm. This study aims to exploring the predictive value for ovarian response by means of
observing the changes of bFSH levels during the in virto fertilization (IVF) cycle so as to provide a theoretical basis for clinical research.Methods:A retrospective analysis was performed on the clinical data of 154 patients who were accepted the IVF-ET at the center of
reproductive medicine in our hospital from January 2012 to December 2012. According to the bFSH levels, the selected patients were
divided into three groups, namely, the groupA (bFSH≥10 IU/L); groupB (8≤bFSH≤10 IU/L) and groupC (bFSH<8 IU/L). Then the
age, the bAFC values, the time and dose of Gn, the rate of fertilization and pregnancy in three groups were compared and evaluated.Results:There were statistically significant differences about the age, the bAFC values, the rate of FSH and LH, the time and dose of Gn,
the numbers of ovum and the rate of pregnancy (P<0.05). But there was no statistically significant difference about the values of LH and
the rate of fertilization in three groups (P>0.05).Conclusion:It is indicated that the values of bFSH could predict the functions of
women's ovary for those who were taken the in vitro fertilization and the levels of bFSH might become an essential item in the future for
the clinical to detect the ovarian reactions of the infertile females during the super ovulation cycles. |
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