| 胡凤新 米玛顿珠 旦曲 郭元 格桑罗布.拉萨地区血浆同型半胱氨酸水平与脑梗死的相关性研究[J].现代生物医学进展英文版,2014,14(3):536-538. |
| 拉萨地区血浆同型半胱氨酸水平与脑梗死的相关性研究 |
| Relationship between the Homocysteine Level and CerebralInfarction in the Lhasa Area |
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| DOI： |
| 中文关键词: 脑梗死 同型半胱氨酸 相关性 高原 |
| 英文关键词: Cerebral infarction Homocysteine Relationship Plateau |
| 基金项目:黑龙江省科技厅重大基金项目(zb08c309)；西藏自治区科技厅课题拉萨市藏族阿尔茨海默病的分子流行病学调查研究 |
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| 中文摘要: |
| 目的：探讨在高原缺氧环境下，研究血浆同型半胱氨酸水平与脑梗死的相关性及临床意义，为高原地区脑梗死的防治提供依
据。方法：随机选取西藏自治区人民医院2011 年04 月-2012 年12 月入院治疗的急性脑梗死患者166 例作为观察组，选择同期就
诊的150 例健康检查者作为对照组，患者就诊第二日清晨采空腹静脉血送检。血浆同型半胱氨酸水平应用循环酶法测定，分析同
型半胱氨酸水平与脑梗死的相关性。结果：观察组患者血浆中同型半胱氨酸水平明显高于对照组，差异显著具有统计学意义(P<0.
01)。结论：高原环境下，高同型半胱氨酸血症是脑梗死的独立危险因素，血浆同型半胱氨酸水平可作为脑血管疾病一级预防的常
规检查指标，以及对缺血性脑卒中的指导治疗有重要意义。 |
| 英文摘要: |
| Objective:To study the relationship and clinical significance between the homocysteine (Hcy) level and cerebral infarction
and to understand the plateau hypoxia environment so as to provide the evidence for the prevention of cerebral infarction in plateau
area.Methods:166 patientswithacute cerebral infarctionwhowere treatedinour hospital fromApril 2011 toDecember 2012were selected to
be the observation group, and another 150 healthy people who were taken the examination were chosen as the control group. Then the
venous blood samples in the second morning and application Circle enzyme were measured by plasma homocysteine level. The relative
factors of the homocysteine (Hcy) level and cerebral infarction were analyzed by SPSS19.0.Results:The homocysteine level of patients
in the observation group was obviously higher than that of the control group with statistically significant difference (P<0.01).Conclusion:It is indicated that the plateau hypoxia environment, high homocysteine levels could be the independent risk factors of cerebral infarction.
Plasma homocysteine levels can be used as a routine examination indicator of the primary prevention on cerebrovascular disease,and take
important significance to guide the treatment of cerebral infarction. |
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