| 唐英1 陈玖2△ 黄平1 杨来启2 李兰兰2.认知疗法联合舍曲林治疗产后抑郁症患者的临床疗效研究*[J].现代生物医学进展英文版,2014,14(2):333-335. |
| 认知疗法联合舍曲林治疗产后抑郁症患者的临床疗效研究* |
| Research on the Clinical Effect of Cognitive Behavioral Therapy Combinedwith Sertralin on the PostpartumDepression* |
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| DOI： |
| 中文关键词: 认知行为疗法 舍曲林 产后抑郁症 临床疗效 |
| 英文关键词: Cognitive behavioral therapy Sertralin Postpartumdepression (PPD) Clinical effect |
| 基金项目:军队中医药科研专项课题（10ZYX108） |
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| 中文摘要: |
| 摘要目的：探讨认知疗法合并舍曲林治疗产后抑郁症患者的临床疗效。方法：将本院2011 年10 月至2012 年7 月收治的76 例
产后抑郁症患者按随机数字表法分为认知疗法合并舍曲林治疗组(试验组，38 例)和舍曲林单独治疗组(对照组，38 例)，进行临床
随机双盲对照试验，采用17 项汉密尔顿抑郁量表(Hamilton Depression Rating Scale，HAMD)、临床整体量表- 疗效总评估量表
(Clinical Global Impression，CGI) 评价和比较两组的临床疗效。结果：(1) 试验组的有效率显著高于对照组，差异有统计学意义
[92.11%vs 81.58 %)，P<0.01]，试验组第2、3 阶段的临床有效率均显著高于对照组，差异有统计学意义(P<0.05)。(2) 与治疗前相
比，两组患者治疗后的HAMD、CGI-SI 总分均降低，差异有统计学意义(P<0.01)；治疗第1、2、3 阶段，试验组HAMD、CGI-SI 减分
值均显著高于对照组，差异有统计学意义(P<0.05)。结论：认知疗法联合舍曲林治疗产后抑郁症的短期治疗内疗效显著优于舍曲
林单独治疗。 |
| 英文摘要: |
| ABSTRACT Objective：To investigate the clinical effect of cognitive behavioral thempy (CBT) combined with Sertralin and single
Sertralin on the postpartum depression. Methods：76 cases of ostpartum depression patients hospitalized from October 2011 to July 2012
were enrolled and divided into the cognitive behavioral thempy combined with Sertralin treated group (experimental group, n=38) and
Sertralin treated group (control group, n=38) by the method of the random number table. Clinical randomized double blind control test
was performed and 17-item Hamilton Depression Rating Scale (HAMD) and Clinical Global Impression (CGI). We used to evaluate and
compare the clinical effect between two groups.Results： (1) The effective rate in the experimental group was significantly higher than
that in the control group [(92.11%vs 81.58 %), P<0.01]. The curative effects in the second and thirdly phase of the experimental group
were significantly better than those of the control group (P<0.05). (2) Compared with prior-treatment, the HAMD and CGI-SI scores of
patients were decreased significantly post-treatment (P<0.01). The reductive score value of HAMD and CGI-SI of experimental group
during three phase were significantly better than thoseof the control group (P<0.05).Conclusion： Cognitive behavioral therapy combined
with Sertralin was superior to single Sertralin in short-termtreatment.of postpartumdepression. |
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