| 张林邓晓玲江艳燕顾雪梅蔡晓军△.埃索美拉唑联合莫沙比利干预老年性反流性食管炎临床研究[J].现代生物医学进展英文版,2014,14(2):320-322. |
| 埃索美拉唑联合莫沙比利干预老年性反流性食管炎临床研究 |
| Clinical Observation of Combined Treatment of Esomeprazole andMosapride in Patients of Senile Reflux Esophagitis |
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| DOI： |
| 中文关键词: 埃索美拉唑 莫沙比利 老年 反流性食管炎 |
| 英文关键词: Esomeprazole Mosapride Senile Reflux esophagitis |
| 基金项目: |
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| 中文摘要: |
| 摘要目的：探讨埃索美拉唑联合莫沙比对老年性反流性食管炎临床疗效。方法：选择符合2003 年反流性食管炎诊断及治疗指南
诊断标准的160 例老年反流性食管炎患者，随机分为治疗组（埃索美拉唑联合莫沙比利）和对照组（奥美拉唑），观察治疗前后内
镜下疗效及症状评分变化。结果：治疗组内镜下病变较对照组显著缓解，总有效率高于对照组，症状评分明显低于对照组，两者间
差异有统计学意义(P |
| 英文摘要: |
| ABSTRACT Objective：To investigate the clinical effect of combined treatment of Esomeprazole and Mosapride on patients of
senile reflux esophagitis.Methods：160 patents with senile reflux esophagitis in accord with the diagnostic and therapic guideline of 2003
were divided into treatment group (Esomeprazole+Mosapride) and control group (omeprazole). The endoscopic effect, symptoms and
scores were evaluated before and after treatment. Results：The endoscopic lesions in treatment group improved significantly than that in
control group, and the total effective rate were higher. The symptomscores of treatment were lower than that in the control group and no
obvious adverse effects were observed during the course of therapy. Conclusion：Combined treatment of Esomeprazole and Mosapride
has good therapeutic effect on patients of senile reflux esophagitis and thus it has high value in clinical application. |
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