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摘要目的：评价药物涂层支架（DES）与金属裸支架（BMS）在急性心肌梗死患者中应用的安全性和有效性。方法：选择2003 年1 月-2010 年12 月，在我院确诊的急性ST 段抬高型心肌梗死（STEMI）167 例患者，其中使用BMS 65 例，DES 102 例。对比分析两组患者住院期间和出院后1 年内的主要心血管或脑血管事件（MAACE）的发生情况及支架内血栓形成的发生率。结果：至随访结束，BMS组有1 例患者猝死，5 例出现复发心绞痛。DES组有1 例突发急性左心衰后死亡，1例复发心绞痛和1 例发生亚急性支架内血栓。结论：DES应用于STEMI具有较好的安全性，其术后MAACE 发生率较BMS 低。

英文摘要:

ABSTRACT Objective：To evaluate and contrast the safety and efficacy of drug-eluting stent (DES) and bare metal stents (BMS) in patients with acute myocardial infarction. Methods：167 cases of patients diagnosed with ST-segment elevation myocardial infarction (STEMI) in our hospital were selected from January 2003 to December 2010, who included 65 cases implanted with BMS and 102 cases implanted with DES. The occurrence of major cardiovascular or cerebrovascular events (MAACE) conditions and stent thrombosis incidence of two groups were analyzed retrospectively and compared respectively during hospitalization and 1 year after discharge.Results： To the end of follow-up, BMS group had one case of sudden death and five cases of recurrent angina, and DES group had one case of sudden death for acute left heart failure, one case of recurrent angina, and one case of subacute stent thrombosis.Conclusion： DES for the treatment of STEMI has good security and lower occurrence rate of the postoperative MAACE incidence compared with BMS.

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