| 梁建军1 田树喜1 王燕平2 于艳红3 苏志红4.阿莫西林克拉维酸钾联合阿奇霉素治疗社区获得性肺炎的临床疗效研究[J].现代生物医学进展英文版,2014,14(2):289-291. |
| 阿莫西林克拉维酸钾联合阿奇霉素治疗社区获得性肺炎的临床疗效研究 |
| Amoxicillin Clavulanic PotassiumCombined with Azithromycin Treatmenton Community-Acquired Pneumonia |
| |
| DOI： |
| 中文关键词: 社区获得性肺炎 阿莫西林克拉维酸钾 阿奇霉素 临床疗效 |
| 英文关键词: Community acquired pneumonia Amoxicillin clavulanic potassium Azithromycin Clinical efficacy |
| 基金项目: |
|
| Hits: 820 |
| Download times: 2471 |
| 中文摘要: |
| 摘要目的：探讨阿莫西林克拉维酸钾联合阿奇霉素治疗社区获得性肺炎（CAP）的临床疗效。方法：选取于2010 年1 月-2012 年1
月收治的CAP 患者145 例，采用随机数字表法将其分为两组，其中治疗组73 例，对照组72 例。治疗组给予阿莫西林克拉维酸钾
联合阿奇霉素治疗，对照组只单纯给予应用阿莫西林克拉维酸钾。两组疗程均为7～14 d。于治疗后比较两组的临床疗效。结果：
（1）治疗组治愈、显效、有效、无效分别为43 例（58.9%）、16 例（21.9%）、8 例（11.0%）、6 例（8.2%）；对照组分别为20 例（27.8%）、26
例（36.1%）、14 例（19.4%）、12例（16.7%）。两组疗效比较，差异有统计学意义（P＜0.05）。（2）治疗组胃肠道反应、静脉滴注局部疼
痛、皮疹的发生分别为6 例（8.2%）、7 例（9.6%）、3 例（4.1%），总不良反应发生率为16 例（21.9%）；对照组分别为5 例（6.9%）、6 例
（8.3%）、3 例（4.2%）、14例（19.4%）。两组不良反应发生率比较，差异无统计学意义（P＞0.05）。结论：阿莫西林克拉维酸钾联合阿
奇霉素治疗CAP 疗效好。 |
| 英文摘要: |
| ABSTRACT Objective：Our study focused on the clinical efficacy of amoxicillin clavulanic potassium acid combined with
azithromycin for the treatment of community-acquired pneumonia (CAP). Methods：145 CAP patients who were admittied during
January, 2010 -January 2012 were selected The patients were divided into two groups using a random number table, including treatment
group (73 cases) and control group (72 cases). The treatment group received amoxicillin clavulanic potassium acid and azithromycin
treatment, control group was applicated only by amoxicillin clavulanic potassium acid. Both groups were treated for 7 ~ 14 days. The
clinical efficacy were compared after treatment.Results： (1) In the treatment group, the amounts of cured, effective and invalid patients
were 43 cases (58.9%), 16 cases (21.9%), 8 cases (11.0%), 6 cases (8.2%) respectively, and they were 20 cases (27.8 %), 26 cases
(36.1%), 14 cases (19.4%), 12 cases (16.7%) in the control group . The difference between the two groups was statistically significant (P
<0.05). (2) In the treatment group, gastrointestinal reactions, local pain induced by intravenous infusion, and rash occurred in 6 cases
(8.2%), 7 cases (9.6%) and 3 cases (4.1%), the total adverse reaction rate was 21.9%(16 cases). However, in the control group they were
five cases (6.9%), 6 cases (8.3%), 3 cases (4.2%), 14 cases (19.4%). The adverse reaction rates were not statistically significant between
two groops(P>0.05). Conclusion：Amoxicillin clavulanic potassium combined with azithromycin treatment has better curative efficacy to
CAP. |
|
View Full Text
View/Add Comment Download reader |
| Close |
|
|
|
