| 潘姿娇 王建红 何敏.几种药物对吗啡相关的条件位置偏好影响的研究进展[J].现代生物医学进展英文版,2014,14(1):187-189. |
| 几种药物对吗啡相关的条件位置偏好影响的研究进展 |
| Research Progress of Drugs Related to Morphine ConditionedPlace Preference |
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| DOI： |
| 中文关键词: 药物 吗啡 条件位置偏好 |
| 英文关键词: Medicine Morphine Condition place preference |
| 基金项目:国家自然科学基金项目（31271168） |
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| 中文摘要: |
| 条件化位置偏好（conditioned place preference，CPP），常用于研究药物成瘾的相关记忆。这里主要综述了一些药物对CPP的
影响。神经肽S，神经肽FF，肌肽，孤啡肽，琢-2 受体激动剂，L- 左旋千金藤啶碱，东莨菪碱，丙戊酸钠，巴氯芬对吗啡CPP 有抑制效
应；聚肌胞苷酸，氟伏沙明和金刚烷胺能增强吗啡CPP；阿坎酸能抑制乙醇和某些类别的滥用药物的条件化奖赏效应，但不影响
吗啡引起的条件化奖赏效应；褪黑激素逆转吗啡诱导的奖赏效应；人重组干扰素- 琢导致吗啡CPP 的恢复。 |
| 英文摘要: |
| Conditioned place preference (cpp)was used in studying drug addiction related to memory. Here we mainly reviewed
the effect of some drugs on cpp. Neuropeptide S and neuropeptide FF, carnosine, opioid peptide nociceptin, 琢-2 agonists, l-stepholidine ,
scopolamine, valproate sodium, baclofen impaired morphine cpp; polyinosinic-polycytidylic acid, fluvoxamine and amantadine anti enhanced
morphine cpp; anti-relapse compound acamprosate suppressed ethanol and certain categories of drug abuse, but had no effect on
morphine cpp; elatonin melatonic reversed of morphine-induced the rewarding effect; recombinant human interferon-琢can retrieved
morphine cpp. |
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