欢迎访问《现代生物医学进展》编辑部！

目的：探讨胎膜早破早产的临床处理方法及其对新生儿的影响。方法：以2009 年3 月至2012 年1 月在我院产科住院的妊娠满28～36+6 周的205 例胎膜早破早产患者为研究对象，针对不同孕周，采用相应的治疗方法，并对其妊娠结局和早产儿的状况进行观察和分析。结果：胎龄28～34+6 周的早产儿并发症的发生率和死亡率分别为52.2%和10%，胎龄35～35+6 周的早产儿并发症的发生率和死亡率分别为32.3%和4.8%，分别明显高于胎龄>36 周出生的早产儿（1.6%和0），差异具有统计学意义(P<0. 05)；但孕周在36 周以上出生的新生儿的并发症的发生率和死亡率与足月出生的新生儿相比无明显差异（P>0.05）。结论：胎膜早破早产是新生儿患病和死亡的主要原因，胎龄越小新生儿的患病率和死亡率越高，对于胎膜早破早产的孕妇，应针对不同孕周采用不同的治疗方法，以延长孕周以降低早产儿的患病率和死亡率。

英文摘要:

Objective: To investigate the clinical treatment and Impact of preterm premature rupture of fetal membranes(PPROM) on newborns. Methods: 205 newborns of PPROM at 28～36+6 weeks of pregnancy between March 2009 to January 2012 in our hospital were included and treated in different methods according to their gestational age. Then the outcome of pregnancy and situation of preterm infants were observed and analyzed. Results: The rate of complications and mortality of the preterm infants was respectively 52.2% and 10% in 28～34 weeks of pregnancy group, 40.3% and 4.8% respectively in 34～35+6 weeks of pregnancy group, they were all significantly higher than those of preterm infants >36 weeks(1.6% and 0, respectively)(P<0.05); However, no significant difference of the rate of complications and mortality of preterm infants was observed between >36 weeks and full-term infants (P>0.05). Conclusions: PPROM is the main reason of morbidity and mortality of newborns. While the smaller of the gestational age, the higher of morbidity and mortality. PPROM should be treated in different methods according to their weeks of pregnancy to extend the gestational age and reduce the morbidity and mortality of preterm infants.

View Full Text View/Add Comment Download reader