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目的：探讨全髋关节置换术治疗晚期非创伤性股骨头缺血性坏死的临床疗效，为临床治疗提供参考依据。方法：将我院进行全髋关节置换术治疗晚期股骨头缺血性坏死患者25 例（30 髋）按病因分三组，A 组酒精性17 例，B 组为激素性6 例，C 组潜水性 2 例，记录各组患者术前、术后的临床症状，患髋功能，X 片等，并进行Harris 评分，对结果进行评价分析。结果：三组术后Harris 评分分别为（89.7±2.8）、（81.5±3.1）分、（87.8±2.9）分，经方差分析，差异有统计学意义(P＜0.05)；三组术后假肢松动髋数率分别为 4.8%、16.7%、0%，经卡方检验，差异有统计学意义(P＜0.05)；三组术后随访3 年总体髋部优良率分别为100%、83.3%、100%，经卡方检验，差异有统计学意义(P＜0.05)。结论：全髋关节置换术治疗晚期非创伤性股骨头缺血性坏死疗效较好，对酒精性病因患者疗效最好。

英文摘要:

Objective: To analyze clinical efficacy of total hip arthroplasty in treatment of advanced non-traumatic osteonecrosis of the femoral head (ONFH). Methods: 25 patients (30 hips) treated by total hip arthroplasty in our department were divided into three groups according to etiology: alcohol group（17 cases）, steroid group（6 cases）, diving group (2 cases）. Preoperative and postoperative clinical data, hip function and X-ray films were analyzed. All the patients were evaluated by Harris score and compared. Results: All patients gained follow-up. Postoperative Harris score of three groups was（89.7±2.8）points,（81.5±3.1）points and（87.8±2.9）points, respectively. The difference was statistically significant (P<0 05). The loosening rate of prosthesis in three groups was 4.8%、16.7% and 0%, respectively. The difference was significant by Chi-square test (P＜0.05). Post-operation general excellent and good ratio of three groups is 100%, 83.3% and 100% after 3 years, respectively. The difference was significant by Chi-square test (P＜0.05). Conclusion: Total hip arthroplasty has better effect in treating advanced non-traumatic ONFH. The clinical efficacy of alcoholic etiology was satisfactory.

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