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焦亦妮1 王喜华1 彭妍1 李有秋2.黄芪注射液联合TP 化疗方案治疗晚期卵巢癌的临床疗效分析*[J].现代生物医学进展英文版,2012,12(27):5284-5287.
黄芪注射液联合TP 化疗方案治疗晚期卵巢癌的临床疗效分析*
Clinical Effect of the Advanced Ovarian Cancer Treated by Huangqi InjectionCombined with TP Regimen*
  
DOI:
中文关键词: 黄芪注射液  TP 方案  晚期卵巢癌
英文关键词: Huangqi injection  TP Regimen  Advanced ovarian cancer
基金项目:湖南省教育厅基金项目资助(09C632)
Author NameAffiliation
JIAO Yi-ni1, WANG Xi-hua1, PENG Yan1, LI You-qiu2 湖南省攸县人民医院妇科 
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中文摘要:
      目的:观察黄芪注射液联合TP 化疗方案治疗晚期卵巢癌的临床疗效及安全性。方法:将62 例晚期卵巢癌患者随机分成两 组,其中31 人为治疗组,接受黄芪注射液联合TP 治疗,31 人采用TP 治疗。从总效率、疾病控制、毒副反应等指标进行评价。结 果:治疗组的总效率、疾病控制、骨髓抑制以及肝肾功能与对照组相比,差异无统计学意义(P>0.05);治疗组的中性粒细胞、心脏 毒性、脱发、肌肉关节疼痛、胃肠道反应与对照组相比,差异有统计学意义(P<0.01)。结论:黄芪注射液联合TP 化疗方案治疗晚期 卵巢癌的临床疗效显著,降低了化疗的毒副反应。
英文摘要:
      Objective: To explore clinical efficacy and safety of advanced ovarian cancer treated by Huangqi injection combined with TP Regimen. Methods: 62 patients with advanced ovarian cancer were randomly divided into the treating group (31people) and control group(31 people). The treating group was treated with Huangqi injection combined with TP Regimen; the control group was only applied to TP Regimen. The clinical efficacy and safety were evaluated by calculating the total effect rate, disease control rate and observing the toxicity reaction. Results: There is no statistical difference in total effect rate, disease control rate, bone marrow supression and function of liver and kidney between the two groups (P >0.05). Compared with control group, the treating group showed significant difference in Neutrocytopenia, cardiac toxicity, Hair loss, Muscle and joint ache, and Gastrointestinal reaction (P <0.05). Conclusion: Huangqi injection plus TP Regimen had markedly clinical efficacy in treating the advanced ovarian cancer. It also plays a role in reducing the toxicities of chemotherapy.
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