Article Summary
武元元1 张选奋2△.病理性瘢痕形成中VEGF 表达及调控的研究进展*[J].现代生物医学进展英文版,2012,12(26):5178-5181.
病理性瘢痕形成中VEGF 表达及调控的研究进展*
Development Study on VEGF Expression and Regulationof Pathological Scar Formation*
  
DOI:
中文关键词: 病理性瘢痕  VEGF  表达  调控
英文关键词: Pathological scar  VEGF  Expression  Regulation
基金项目:国家自然科学基金资助项目(30672185)
Author NameAffiliation
WU Yuan-yuan1,ZHANG Xuan-fen2△ 兰州大学第二临床医学院 
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中文摘要:
      病理性瘢痕一直是整形外科乃至整个外科界研究的热点,由于其发病机制十分复杂,迄今尚无明确的病因学诊断和有效的 治疗方法。VEGF作为目前活性最强的血管生长因子,与病理性瘢痕的发生、发展关系密切。研究病理性瘢痕形成过程中VEGF的 表达及调控机制,有助于阐明病理性瘢痕的发病机制,为预防和治疗病理性瘢痕提供依据。
英文摘要:
      Pathological scar is still the research focus in the plastic surgery and even all surgical field.Due to its very complex pathogenesis, there is no clear etiology diagnosis and effective treatment at present. VEGF as the most active vascular growth factor has close relationship with the occurrence and development of pathological scars. To study the VEGF expression and regulation mechanism in the course of pathological scar formation will not only be favorable to elucidate its pathogenesis but also provide theoretical foundation for its prevention and treatment.
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