张桂霞吴凯△ 韦虎高音李金生王德荣.扩张型心肌病患者恶性室性心律失常与心率变异性关系分析[J].现代生物医学进展英文版,2012,12(26):5085-5087. |
扩张型心肌病患者恶性室性心律失常与心率变异性关系分析 |
Analysis of the Relation between HRV and Malignant VentricularArrhythmia in Patient with Dilated Cardiomyopathy |
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DOI: |
中文关键词: 扩张型心肌病 心率变异性 自主神经功能 恶性室性心律失常 |
英文关键词: Dilated cardiomyopathy(DCM) Heart rate variability(HRV) Autonomic nerve function Malignant ventricular arrhythmia(
MVA) |
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中文摘要: |
目的:了解扩张型心肌病患者恶性心律失常(MVA)与心率变异性( heart rate variability,HRV) 的关系,探讨扩心病患者体内
自主神经变化的临床意义。方法:选择扩心病患者48例作为研究对象,同时按照年龄配对,取48例正常者作为对照组,对其行24
小时动态心电图检查,依据其是否出现恶性心律失常分为恶性室性心律失常(MVA+)组及单纯扩张型心肌病(MVA-)组,分析组间
HRV的差异。结果:与对照组比较,单纯扩张型心肌病(MVA-)组HRV时域指标(SDNN、SDANN、RMSSD)均有降低(P<0.05)L 与
(MVA-)组相比,恶性室性心律失常(MVA+)组HRV相关指标进一步降低(P<0.05)。结论:自主神经功能异常是扩张型心肌病患者
恶性心律失常的重要危险因子,可能可以用HRV预测其发生恶性心律失常危险性。 |
英文摘要: |
Objective: To analyze the relation between Heart Rate Variability (HRV) and malignant ventricular arrhythmia(MVA)
in patient with dilated cardiomyopathy (DCM), and to provide clinic basis for predicting the risk of death. Methods: We divide the 48
patients with dilated cardiomyopathy into 2 groups according to MVA, we also collect 48 normal people as control. They are MVA(+)
group, MVA(-) group and normal control group. We analyze the difference of HRV indexes such as SDNN, SDANN and RMSSD among
the 3 groups. Results: The indexes of SDNN, SDANN and RMSSD in MVA (+) group are lower than those in MVA (-) group, and the
indexes of HRV in MVA (-) group is lower than normal group using ANOVA. Conclusions: MVA is closely related to the decrease of
HRV. HRV might be used to predict the incidence of MVA and sudden death in patient with DCM. |
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