| 秦志华肖翊君李虹吴晋莉.高压氧治疗重型颅脑损伤的临床疗效观察[J].现代生物医学进展英文版,2012,12(25):4885-4888. |
| 高压氧治疗重型颅脑损伤的临床疗效观察 |
| Observation of Clinical Efficacy of Hyperbaric Oxygen on SevereTraumatic Brain Injury |
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| DOI： |
| 中文关键词: 高压氧 重型颅脑损伤 临床疗效 |
| 英文关键词: Hyperbaric oxygen Severe traumatic brain injury Clinical efficacy |
| 基金项目: |
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| 中文摘要: |
| 目的：观察高压氧辅助治疗重型颅脑损伤的临床疗效。方法：68 例重型颅脑损伤患者随机分为观察组和对照组各34 例，所
有患者均根据病情选择手术或保守治疗，观察组在患者病情稳定后加用高压氧辅助治疗，治疗结束后比较两组患者的临床疗效。
结果：观察组治疗有效率为91.2%，显著高于对照组的76.5% (P<0.05)；治疗后1 周和2 周观察组的GCS 评分均显著高于对照组
(P<0.05)，治疗后6 个月观察组的GOS 评分显著高于对照组(P<0.05)；治疗后两组患者脑动脉血流速度均较治疗前有明显的改善
(P<0.05)，且观察的的改善情况优于对照组。结论：选择高压氧辅助治疗重型颅脑损伤的临床疗效好，可改善患者的临床情况和预
后，值得临床应用。 |
| 英文摘要: |
| Objective: To observe the clinical effect of hyperbaric oxygen (HBO) on severe traumatic brain injury(STBI). Methods:
68 cases of patients with STBI were randomly divided into observation group and control group, 34 cases in each group. All the patients
were given surgical or conservative treatment according to pathogenesis. Patients in the observation group were given hyperbaric oxygen
therapy when patient's condition was stable and ruled out the contraindications. The clinical efficacy of two groups were compared after
treatment. Results: The total effective rate of observation group was 91.2%, which was significantly higher than that of control group
(76.5%, P<0.05). The GCS score of observation group was markedly higher than that of control group 1 and 2 weeks after treatment(P<0.
05); The GOS score of observation group was statistically higher than that of control group six months after treatment (P<0.05). After
treatment, the flow velocity of cerebral artery were both significantly improved in two groups (P<0.05), the effect of observation group
was much better than the control group. Conclusion: Treatment with hyperbaric oxygen is able to improve the clinical situation and prognosis
of severe traumatic brain injury, which is worth being generalized. |
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