| 杨欣璐孙敬霞△ 蔡丽瑛.辅酶Q10 对子痫前期中氧化应激的防治作用的研究进展[J].现代生物医学进展英文版,2012,12(24):4765-4768. |
| 辅酶Q10 对子痫前期中氧化应激的防治作用的研究进展 |
| The Evolution of the Prevention and Treatment of Coenzyme Q10Preeclampsia on Oxidative Stress in Preeclampsia |
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| DOI： |
| 中文关键词: 辅酶Q10 氧化应激 子痫前期 |
| 英文关键词: Coenzyme Q10 Oxidative Stress Preeclamipsia |
| 基金项目: |
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| 中文摘要: |
| 子痫前期是导致全球孕产妇和围生儿发病和死亡的主要原因之一。子痫前期的病因至今尚未明确，但是大量研究已证实多
系统的氧化应激与子痫前期发病机制有关。辅酶Q10 是目前受到广泛关注的一种抗氧化剂，并且已有辅酶Q10 药品制剂问世。本
文从细胞水平简要总结了氧化应激与子痫前期发病机制的关系，并讨论了辅酶Q10 对子痫前期中氧化应激的防治作用。希望为
子痫前期的早期治疗及改善预后提供新的思路。 |
| 英文摘要: |
| Preeclampsia is a major cause of maternal and fetal morbidity in the world. Although the etiology of preeclampsia is
still unclear, a large number of researches have confirmed that multi-system oxidative stress (OS) is related to the pathogenesis of
preeclampsia. Coenzyme Q10 is an antioxidant that is widely concerned now, and has been made into pharmaceutical products. This article
has made a brief summary about relationships between OS and preeclampsia in cellular level, and has discussed the action of CoQ10
on OS in preeclampsia. We hoped for providing the new ideas to the early treatment and and the improvement of the prognosis in
preeclampsia. |
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