| 何建国1 马书明1 郑超1 陈敏2 刘芳3.高血压脑出血后血浆脂联素浓度变化及其与C- 反应蛋白相关性的研究*[J].现代生物医学进展英文版,2012,12(24):4725-4727. |
| 高血压脑出血后血浆脂联素浓度变化及其与C- 反应蛋白相关性的研究* |
| Change of Plasma Adiponectin Concentration in Hypertensive IntracerebralHemorrhage and its Correlation with C-Reactive Protein |
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| DOI： |
| 中文关键词: 高血压脑出血 脂联素 C- 反应蛋白 相关性 |
| 英文关键词: Cerebral hemorrhage Adiponectin CRP Correlation |
| 基金项目:重庆市卫生局指导性课题项目（2010-2-204） |
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| 中文摘要: |
| 目的：探讨高血压脑出血后血浆脂联素（APN）浓度变化及其与C- 反应蛋白水平的相关性。方法：高血压脑出血病例82 例列
入研究组，健康者80 例列入对照组，所有受试者均于发病6 小时内抽血检测APN 和C- 反应蛋白（CRP）。结果：研究组患者血清
APN 水平明显低于对照组，CRP 水平明显高于对照组，差异有统计学意义（P<0.05）。随着高血压等级的升高，研究组患者APN 值
逐渐下降，CRP 水平逐渐上升，但APN 与CRP 值的变化无显著差异（P>0.05）。结论：高血压脑出血后患者血浆脂联素浓度变化
与CRP 具有负相关性。 |
| 英文摘要: |
| Objective: To discuss the changes in hypertensive cerebral hemorrhage, plasma adiponectin (APN) concentration and
inflammatory factors in the correlation. Methods: 82 cases of hypertensive intracerebral hemorrhage cases were included in study group,
of health were included in control group, all subjects were phlebotomized within six hours of onset for the detection of APN and C-reactive
protein (CRP). Results: The study group of patients with APN was significantly lower than the control group, significantly higher
than that of CRP values, data were statistically significant differences (P<0.05). With the rise of blood pressure levels of the study group
patients with APN value gradually decreased, CRP values gradually increased, but the change of APN and CRP values was no significant
difference (P>0.05). Conclusion: The plasma adiponectin concentration in patients with hypertensive intracerebral hemorrhage was negatively
correlated with serum level of CRP. |
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