孔琳谭芸龙俊青宋良邓童宁.C- 反应蛋白检测在胎膜早破孕妇中的临床意义[J].现代生物医学进展英文版,2012,12(23):4470-4472. |
C- 反应蛋白检测在胎膜早破孕妇中的临床意义 |
The Clinical Significance of C-Reactive Protein (CRP) Detection in PregnantWomen with Premature Rupture of Membranes |
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DOI: |
中文关键词: C 反应蛋白 胎膜早破 临床意义 感染 |
英文关键词: C-reactive protein(CRP) Premature rupture of membranes(PROM) Clinical significance Infection |
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中文摘要: |
目的:探讨C 反应蛋白(CRP)检测在足月胎膜早破(PROM)孕妇中的临床意义。方法:选取足月胎膜早破(PROM)孕妇50 例为
实验组,并根据破膜时间将足月破膜孕妇分为3 个亚组;并选取同期住院的正常孕妇30 例为对照,采用高敏CRP 试剂盒,测定不
同组别孕妇中CRP 水平。结果:入院时,胎膜早破各亚组中CRP 水平明显高于对照组,具有显著统计学意义(P<0.05);同时随着破
膜时间的增加,各亚组中的CRP 水平及WBC 计数也逐渐升高,且3 个亚组之间也分别存在统计学差异(P<0.05)。在应用抗生素
3d 后,CRP 出现显著下降,与正常组相比未见明显差异(P>0.05);WBC 计数在应用抗生素后的3d 时间出现下降,但与入院前相比
未见明显统计学差异。结论:CRP 检测在判断孕妇胎膜早破、指导临床用药方面具有较高的临床价值,可作为常规检查项目。 |
英文摘要: |
Objective: To investigate the clinical significance of C-reactive protein (CRP) detection in pregnant women with
premature rupture of membranes (PROM) of full-term pregnancy. Methods: Compared with control group concluding 30 cases of normal
pregnant women, there are 50 cases with premature rupture of membranes (PROM) of full-term pregnancy in the experiment group which
was divided into 3 subgroups according to the time in remature rupture of membranes, and high sensitivity CRP kit was to determine the
CRP level in the different groups of pregnant women. Results: Compared with the control group, the CRP levels in the patients with
PROM were higher significantly in the subgroups (P<0.05) at the time of admission. After the application of antibiotics for 3 days, CRP
levels decreased significantly, which shows no significant difference (P>0.05) compared with the control group; and WBC count also
declined in the time of 3d after antibiotics using, but there were no significant statistical difference compared with time of admission.
Conclusion: CRP testing can be as a routine examination in determining the pregnant women with PROM, shows the high clinical value. |
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