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目的：探讨尿微量蛋白联合血清纤维蛋白原在冠心病的诊断价值。方法：选取同期在我院治疗的24 例稳定型心绞痛的患者，36 例诊断为不稳定型心绞痛的患者和30 例诊断为急性心肌梗死的患者，并选择同期30 例来我院体检健康志愿者为对照组。分析以上4 组患者发病时尿微量蛋白及血清纤维蛋白原的变化情况。结果：与对照组比，3 个冠心病组的尿微量蛋白及血清纤维蛋白原的含量显著升高(P<0.05)，与稳定型心绞痛组比，不稳定型心绞痛组的尿微量蛋白及血清纤维蛋白原的含量显著升高(P<0. 05)；与不稳定型心绞痛组比，急性心梗的尿微量蛋白及血清纤维蛋白原的含量显著升高(P<0.05)。3 组病患的尿微量蛋白及血清纤维蛋白原之间呈正相关关系(r=0.852,P<0.05)。结论：心肌梗死和心绞痛患者尿微量蛋白及血清纤维蛋白原含量较健康成人含量高，提示尿微量蛋白及血清纤维蛋白原的含量有助于对心肌梗死和心绞痛的诊断，对急性心肌梗死的诊断价值较高。

英文摘要:

Objective: To explore the detection value of urinemicroalbumin and serum fibrinogen in coronary heart disease. Methods: we chose 30 acute myocardial infarction patients as a group, 36 unstable angina patients at the same period in our hospital as a group, and 24 stable angina patients as a group, 30 healthy volunteers as control group. Analyze the changes about urine microalbumin and serum fibrinogen in 4 group patients. Results: The urine microalbumin and serum fibrinogen were higher in 3 coronary heart disease groups(P＜ 0.05). Compared with stable angina group, urine microalbumin and serum fibrinogen were higher in unstable angina group (P＜0.05). Compared with unstable angina group, urine microalbumin and serum fibrinogen were higher in acute myocardial infarction group (P＜ 0.05). Conclusions: Urine microalbumin and serum fibrinogen in coronary artery disease patients were higher than in healthy adults. This study suggests that there may be a relationship between levels of urine microalbumin and serum fib- rinogen with the development of coronary heart disease.

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