徐义喜栾天竹△ 周立君徐卿璐黄杰.内皮祖细胞在支架术后再内皮化中应用的研究进展[J].现代生物医学进展英文版,2012,12(19):3774-3778. |
内皮祖细胞在支架术后再内皮化中应用的研究进展 |
Research of the Application of Endothelial Progenitor Cells in the StentReendothelialization |
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DOI: |
中文关键词: 内皮祖细胞 支架术后再内皮化 支架内再狭窄 |
英文关键词: Endothelial progenitor cells Re-endothelialisation In-stent restenosis |
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中文摘要: |
经皮冠状动脉介入治疗的应用改善了冠心病患者的临床症状及预后,但现在困扰人们的问题是作为其术后并发症之一的
支架内再狭窄发病率仍然很高。大量的研究证实,内膜增生在支架内再狭窄的形成中起主导作用,所以提高受损内膜再内皮化的
速度是防止支架内再狭窄的一个重要措施。新近的研究表明,内皮祖细胞能参与损伤后血管内皮修复, 促进受损血管内膜的再内
皮化,因此,在防止支架内再狭窄中将得到进一步的研究与应用。因此,本文就内皮祖细胞在支架术后再内皮化中应用的研究进展
做一综述。 |
英文摘要: |
The application of Percutaneous coronary intervention (PCI) in patients with coronary heart disease improved their
clinical symptoms and prognosis, but the puzzled problem is that stent restenosis as the postoperative complications after PCI is still very
common.Intimal hyperplasia plays a very important role in in-stent restenosis,so it is essential to improve the impaired endometrial
endothelialization to prevent in-stent restenosis .Endothelial progenitor cells (EPCs) with its good application in preventing in-stent
restenosis. The latest research indicates that EPCs participate in endothelial repair after injury, and will greatly contribute to the impaired
vascular neointima re-endothelialization. Thus, this article focus on the application of Endothelial progenitor cells in the stent
reendothelialization. |
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