| 谢康宁1 申广浩1 田越2 刘娟1 闫一力1 罗二平1 许全盛3.糖尿病大鼠内嗅皮层神经元放电与场电位相干性研究[J].现代生物医学进展英文版,2012,12(16):3071-3073. |
| 糖尿病大鼠内嗅皮层神经元放电与场电位相干性研究 |
| The Spike-field Coherence Analysis of Neural Signals From EntorhinalCortex of Diabetic Rats |
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| DOI： |
| 中文关键词: 糖尿病 相干 内嗅皮层 |
| 英文关键词: Diabetes Coherence Entorhinal cortex |
| 基金项目:国家自然科学基金（31000491） |
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| 中文摘要: |
| 目的：通过分析神经元放电与场电位的相干性，探讨内嗅皮层神经元放电与场电位的关系。方法：10 只成年大鼠随机分2
组，一组糖尿病建模，另一组作为对照，记录对照组和糖尿病组大鼠的内嗅皮层神经元放电锋电位和场电位，利用点过程谱分析
方法对神经元放电与场电位相干性进行分析对比。结果：糖尿病大鼠麻醉神经元放电与场电位的相干性明显低于对照组（P<0.01)。
结论：糖尿病大鼠内嗅皮层神经元功能受到损害。 |
| 英文摘要: |
| Objective: To study neural signal coordination of diabetic rats by analyzing the spike-field coherence (SFC). Methods:
The 10 adult rats were divided randomly into two groups: 5 in control group and 5 in diabetic group. Local field potentials and neuronal
spikes were recorded from the entorhinal cortex. Using the spectrum analysis method of point process, the SFC was conducted for signals
fromentorhinal cortex in both groups. Results: The SFCwas significantly lower in diabetic group than in control group (P<0.01). Conclusion:
The results suggest the impairment of neural functioning for diabetic rats. |
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