| 阮光强王羡强陈国军马海燕马敬伟.胸水中VEGF、TNF-α 的检测对良恶性胸水的鉴别诊断意义[J].现代生物医学进展英文版,2012,12(15):2952-2953. |
| 胸水中VEGF、TNF-α 的检测对良恶性胸水的鉴别诊断意义 |
| Differential Diagnostic Significance of Determination of VEGF, TNF-α inPleural Effusion between Benign and Malignant Hydrothora |
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| DOI： |
| 中文关键词: 血管内皮生长因子 肿瘤坏死因子 胸水 诊断意义 |
| 英文关键词: VEGF TNF-α Hydrothora Diagnostic significance |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨检测胸水中血管内皮生长因子（VEGF）、肿瘤坏死因子（TNF-α）水平对良恶性胸水的鉴别诊断意义。方法：采用酶
联免疫检测法（ELISA）测定34 例良性胸腔积液患者和44 例恶性胸腔积液患者胸水中VEGF、TNF-α 水平。结果：良性胸腔积液
组患者胸水中TNF-α 水平显著高于恶性胸腔积液组（P<0.05）；良性胸腔积液组患者胸水中VEGF 水平显著低于恶性胸腔积液组
（P<0.05）。结论：胸水中VEGF、TNF-α 水平的检测对良、恶性胸水患者具有鉴别诊断意义。 |
| 英文摘要: |
| Objective: To explore the differential diagnostic significance of determination of VEGF, TNF-α in pleural effusion
between benign and malignant hydrothora. Methods: The levels of VEGF, TNF-αin pleural effusion of 34 patients with benign
hydrothora, 44 patients with malignant hydrothora were detected by ELISA. Results: The levels of TNF- α in pleural effusion were
significantly increased in patients with benign hydrothora in comparison with those of patients with malignant hydrothora, and the levels
of VEGF were significantly decreased in patients with benign hydrothora in comparison with those of patients with malignant hydrothora,
the difference was statistically significant (P<0.05). Conclusion: The levels of VEGF, TNF-α in pleural effusion may be used as an
marker in the differential diagnostic significance of benign and malignant hydrothora. |
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