| 祝宝钦 黄燕芳 杨晓煜.印迹基因Igf2 对胎盘发育和胎儿生长的影响[J].现代生物医学进展英文版,2012,12(14):2778-2800. |
| 印迹基因Igf2 对胎盘发育和胎儿生长的影响 |
| The Influence of Imprinted Gene Igf2 on Placental Developmentand Fetal Growing |
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| DOI： |
| 中文关键词: 印迹基因 Igf2 胎儿生长 胎盘发育 |
| 英文关键词: Imprinted gene Igf2 Placental development Fetal growing |
| 基金项目:国家自然科学基金（31071311）；福建省杰出青年科学基金（2009J06017） |
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| 中文摘要: |
| 基因组印迹是哺乳动物正常生长发育和行为的基础。印迹基因胰岛素样生长因子2(insulin-like growth factors II，Igf2）对胎
盘及胎儿的营养供应起着不可或缺的影响。它影响胎盘的大小、形态和营养转运功能，进而影响胎儿生长的营养供应。因此Igf2
表达的变化对发育编程具有重要意义，对胎盘发育和胎儿生长起着重要的作用。 |
| 英文摘要: |
| Genomic imprinting is the basic of normal growing development and activity in mammal. Insulin-like growth factors
II （Igf2）plays an important role in nutrition supply of placenta and fetus. It affects the size, modality and nutrient transfer function in
placenta, and then influence nutrient transfer of fetus growing. Therefore, the changes of Igf2 have great significance on developmental
programming, also is important to placental development and fetal growing. |
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