王健 邹仲敏 赵吉清.MiR-203 及其调控机制的研究进展[J].现代生物医学进展英文版,2012,12(14):2743-2747. |
MiR-203 及其调控机制的研究进展 |
The Research Progress of MiR-203 and its Regulation Mechanisms |
|
DOI: |
中文关键词: MiR-203 调控 皮肤 |
英文关键词: MiR-203 Regulation Skin |
基金项目:国家自然科学基金面上项目(31171118) |
|
Hits: 741 |
Download times: 907 |
中文摘要: |
MicroRNA(miRNA)是一种长18-25 个碱基的单链非编码RNA,其广泛参与机体众多病理、生理过程。MiR-203 是一种上皮
组织特异性表达的miRNA。研究发现miR-203 在皮肤发育、皮肤相关疾病、上皮组织肿瘤等病理、生理过程中发挥重要调控作用。
一些疾病的研究还发现了miR-203 与表观遗传学机制的相互作用, 而miR-203 调控机制的研究集中在P63、SOCS-3 及相关的信
号通路等方面。 |
英文摘要: |
MicroRNAs (miRNA) are 18-25-nucleotide, single-stranded, non-coding RNAs that participate in many pathological
and physiological processes of the body. MiR-203 is a miRNA specially expressed in epithelial tissue. Researches show that miR-203
plays an important role in skin development, skin-related diseases, epithelial tumors and other pathological and physiological processes.
The interaction between miR-203 and epigenetic mechanisms is also discovered in the researches on some diseases, while the researches
on the regulation mechanisms of miR-203 focus on P63, SOCS-3 and related signal pathways. |
View Full Text
View/Add Comment Download reader |
Close |