| 张雄军王德明△.POCD 发病机制的研究进展[J].现代生物医学进展英文版,2012,12(10):1986-1988. |
| POCD 发病机制的研究进展 |
| Research Advance in the Pathogenesis Studyof Postoperative Cognitive Dysfunction |
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| DOI： |
| 中文关键词: POCD 发病机制 手术 麻醉 |
| 英文关键词: POCD Pathogenesis Anesthesia Surgery |
| 基金项目: |
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| 中文摘要: |
| 术后认知功能障碍（Postoperative Cognitive Dysfunction，POCD）的特征性表现是麻醉和手术后认知功能的持续性下降。这种
多认知领域的功能需要感觉和广泛的神经学检测来评估，由于不同的检测仪器、不同的时间点和应用不同的统计学方法，因而对
POCD 一直没有统一的定义，各POCD 间的研究也缺乏比较性。因此，进一步阐述POCD 的影响因素及发病机制，有利于对
POCD 的研究建立标准的检测、诊断和防治方法。 |
| 英文摘要: |
| POCD is characterized by a persistent decline in cognitive function following anesthesia and surgery, identified by
preoperative and postoperative cognitive testing. This testing requires a sensitive and comprehensive neuropsy-chological test battery
assessing a variety of cognitive domains. However, the investigation and diagnosis of POCD is hampered by the absence of a consensus
regarding the tests to be used as well as the operational definition of POCD. Consequently, the comparison between studies investi-gating
POCD is difficult.Therefore, further elaboration of POCD factors and pathogenesis, will help establish standards for POCD detection,
diagnosis and control methods. |
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