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目的：探讨高脂血症对直肠癌不同手术方式合并症的影响。方法：回顾分析行开腹或腹腔镜直肠癌根治术治疗的255 例患者的临床资料，比较伴或不伴高脂血症患者的围手术期指标，采用卡方检验或t 检验进行统计学分析。结果：与非高脂血症组患者相比，高脂血症组术中出血量大(P<0.01)，术后恢复进食时间长(P<0.01)，术后住院时间增加(P<0.05)，拔除引流管时间延长 (P<0.01)，切口脂肪液化并发症增多(P<0.05)。与开腹组相比，腹腔镜组术中出血量少(P<0.01)，手术时间、术后恢复进食时间、术后住院时间、拔除引流管时间均明显缩短(均为P<0.01)，切口脂肪液化发生率低(P<0.05)。在腹腔镜手术组，与正常血脂组相比，高脂血症患者术中出血量较大(P<0.01)，余指标无明显差异。结论：高脂血症可引起直肠癌手术出血量增加、术后恢复慢、伤口脂肪液化发生率高，腹腔镜手术可加快患者术后恢复。

英文摘要:

Objective: To investigate the effects of hyperlipidemia on postoperative complications in patients of rectal cancer with different surgical. Methods: A retrospective analysis on clinical data of 255 patients underwent open or laparoscopic rectal cancer surgical were reviewed. Perioperative indicators of patients with or without hyperlipidemia were compared. Chi-square test or t test was used for statistical analysis. Results: Compared to non-hyperlipidemic patients, hyperlipidemia group had more blood loss volume (P<0.01), more postoperative recovery time for eating (P<0.01), increased postoperative hospital stay (P<0.05) , prolonged removal of drainage tube (P<0.01), increased fat liquefaction (P<0.05). Compared with laparotomy, laparoscopic group had less blood loss (P<0.01), operative time, postoperative recovery feeding time, postoperative hospital stay, and time to drainage tube removal were significantly reduced (all P<0.01), low incidence of wound fat liquefaction (P<0.05). In the laparoscopic surgery group, compared with normal cholesterol, higher blood loss in patients with hyperlipidemia (P<0.01), other indicators showed no significant difference. Conclusion: Hyperlipidemia can cause increased bleeding after rectal cancer surgery, and postoperative recovery was slow, the high incidence of wound fat liquefaction, Laparoscopic surgery can accelerate postoperative recovery.

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