| 钟华毕胜△.G-CSF 在缺血性脑卒中动物模型治疗中的研究进展[J].现代生物医学进展英文版,2012,12(9):1794-1796. |
| G-CSF 在缺血性脑卒中动物模型治疗中的研究进展 |
| Advances of granulocyte-colony stimulating factor in the Treatmentof Ischemic Cerebral Vascular Disease |
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| DOI： |
| 中文关键词: 粒细胞集落刺激因子 缺血性脑血管病 脑卒中模型 |
| 英文关键词: Granulocyte-colony stimulating factor（G-CSF） Ischemic cerebral vascular disease Stroke model |
| 基金项目: |
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| 中文摘要: |
| 粒细胞集落刺激因子（G-CSF）是细胞生长因子家族中的一员,主要功能是刺激细胞增殖分化降低细胞凋亡。近年来许多缺
血性脑卒中的实验研究显示其能有效改善由于脑卒中等中枢神经系统疾病所致的神经功能缺损,G-CSF 用于缺血性脑卒中的治
疗具有广阔的前景。文章从G-CSF 在缺血性脑卒中的研究进展及其作用机制等方面进行综述。 |
| 英文摘要: |
| Granulocyte colony-stimulating factor (G-CSF) is a member of the cytokine family of growth factors. G-CSF stimulates
the proliferation, survival, and maturation of cells. Recent experimental studies on the G-CSF in the treatment of ischemic cerebral
vascular disease have shown that G-CSF can improve neurologic impairment. G-CSF have broad prospects to be used in the treatment of
ischemic cerebral vascular disease. This review focus on the use of G-CSF in ischemic cerebral vascular disease, and the mechanism of
their action. |
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