| 方刚1 梁丹1 刘群华1 钟璐2 黎燕玲2△.壮药金回合剂治疗宫颈上皮内瘤变、HPV 感染合并宫颈炎症
的疗效分析[J].现代生物医学进展英文版,2012,12(8):1530-1532. |
| 壮药金回合剂治疗宫颈上皮内瘤变、HPV 感染合并宫颈炎症
的疗效分析 |
| Efficacy Analysis of Zhuang Medicine Jin-hui Mixture in TreatingCervical Intraepithelial Neoplasia HPV Infection Associatedwith Cervical Inflammation |
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| DOI： |
| 中文关键词: 宫颈上皮内瘤变 HPV 感染 宫颈炎症 壮药金回合剂 疗效 |
| 英文关键词: Cervical intraepithelial neoplasia HPV infection Cervical inflammation Zhuang medicine jin-hui mixture Efficacy |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨壮药金回合剂治疗宫颈上皮内瘤变、HPV 感染合并宫颈炎症的疗效。方法：将符合纳入标准的宫颈上皮内瘤变、
HPV 感染合并宫颈炎症患者，随机分为2 组，各35 例。观察组：壮药金回合剂宫颈上药，qod；对照组：安达芬拴宫颈上药，qod，比
较两组临床疗效。结果：CINⅠ，观察组有效率为89.29%，对照组为65.38%，差异有显著性(P＜0.05)；而CINⅡ差异无显著性。HPV
转阴，观察组转阴率为68.57%，对照组为45.71%，差异有显著性(P＜0.05)；宫颈炎改善情况比较，观察组有效率为94.29%，对照
组为77.14%，差异有显著性(P＜0.05)。全部患者在治疗过程中均未发现需要注意的不良反应。结论：壮药金回合剂治疗宫颈上皮
内瘤变、HPV 感染合并宫颈炎症，可恢复宫颈屏障功能，HPV 转阴率高，疗效好。 |
| 英文摘要: |
| Objective: To investigate the effect of Zhuang medicine Jin-hui mixture in treating cervical intraepithelial neoplasia,
HPV infection with cervical inflammation. Methods: Patients who got cervical intraepithelial neoplasia and HPV infection associated
with cervical inflammation, were divided into two groups randomly, 35 cases in each group. Observer group were treated with Zhuang
medicine Jin-hui mixture on the cervix, qod. Control group were treated with Recombinant human Interferon α -2b Suppository, on the
cervix, qod. Compare the clinical efficacy between the two groups. Results: For CINⅠ, the efficiency was 89.29% in the observation
group, and 65.38% in the control group, with significant difference (P<0.05); and for CIN Ⅱ, there was no significant difference. There
was a HPV negative rate of 68.57% in the observation group, and 45.71% in the control group; the difference was significant (P<0.05). In
the observation group , 94.29% had cervicitis improved, but only 77.14% in the control group were improved, and the difference was
significant (P<0.05). There were no adverse reactions that should be noted in the whole treating. Conclusion: Zhuang medicine Jin-hui
mixture has good effect in treating cervical intraepithelial neoplasia, HPV infection associated with cervical inflammation. It could help
restoring the function of the cervix. |
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