| 陈琦贾宇臣王利郑源强.荧光原位杂交技术及其在医学诊断上的应用[J].现代生物医学进展英文版,2012,12(5):988-991. |
| 荧光原位杂交技术及其在医学诊断上的应用 |
| Fluorescence in Situ Hybridization and it's Medical Application |
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| DOI： |
| 中文关键词: 荧光原位杂交（FISH） 癌症 产前诊断 医学诊断 |
| 英文关键词: Fluorescence in situ hybridization FISH Cancer Prenatal diagnosis Medical diagnostics |
| 基金项目:内蒙古医学院博士启动金（nybq2010cq） |
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| 中文摘要: |
| 荧光原位杂交技术是近年来生物学领域发展起来的将经典的细胞遗传学与分子遗传学结合起来一项新技术。该技术具有
广泛的应用潜力，在细胞生物学、分子生物学、医学等众多领域快速发展。本文介绍了荧光原位杂交技术的基本原理和操作方法，
并对该技术目前的发展状况以其在医学诊断上的应用进行了阐述。 |
| 英文摘要: |
| Fluorescence in situ hybridization (FISH) is a new technique developed in the field of biology in recent years. FISH is
a powerful technique that covers a gap between classical cytogenetic and molecular-genetic techniques. By the broad spectrum of
application possibilities it leads to important new developments in cytogenetics, medical diagnostics, molecular biology and so on. This
review give a brief overview of the principle, operational approach, developments of FISH and it's medical applications. |
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