| 李猛岳强金慧.急诊PCI 治疗中应用血栓抽吸术及主动脉内球囊反搏术
与血浆脑钠肽水平、心功能参数的关系[J].现代生物医学进展英文版,2012,12(4):687-689. |
| 急诊PCI 治疗中应用血栓抽吸术及主动脉内球囊反搏术
与血浆脑钠肽水平、心功能参数的关系 |
| Relationship of Combined Application of Intra-Aortic BalloonCounterpulsation and Thrombus Aspiration, the Level of BNP and theParameter of Heart Function in Emergent Percutaneous Coronary Intervention |
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| DOI： |
| 中文关键词: 主动脉内球囊反搏术 血栓抽吸术 冠状动脉介入治疗 血浆脑钠肽水平 心功能参数 |
| 英文关键词: Intra-aortic balloon pump Thrombus aspiration Percutaneous coronary intervention BNP Parameter of heart function |
| 基金项目: |
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| 中文摘要: |
| 目的：观察血栓抽吸术与主动脉内球囊反搏术（IABP）联用在急诊冠状动脉介入治疗（PCI）的疗效。方法:ST 段抬高型急性心
肌梗塞（AMI）行急诊冠状动脉造影提示大量血栓征象、并行血栓抽吸术患者98 例，随机分为实验组和对照组，实验组术前行
IABP 后联合血栓抽吸；对照组仅进行血栓抽吸。观察两组患者的BNP 及心功能参数。结果：术后24 小时两组BNP 有普遍升高趋
势，对照组升高更明显(P＜0.01)，术后2 周普遍回降，实验组下降更明显(P＜0.01)；2 周后实验组的心脏指数（CI）、每搏指数（SI）、
混合静脉血氧饱和度（SvO2）均高于对照组（P＜0.01)。结论：对于行急诊冠状动脉介入治疗的患者联合使用主动脉内球囊反搏术
和血栓抽吸术，可以明显改善患者的心肌缺血情况，增加冠脉灌注，有利于患者心功能的恢复。 |
| 英文摘要: |
| Objective: To investigate the efficiency of combined use of intra-aortic balloon pump (IABP) and thrombus aspiration
in primary percutaneous coronary intervention (PCI). Methods: A total of 98 patients with acute ST segment elevation myocardial
infarction (STEMI) were found to have bulky thrombi by emergent PCI, and then treated with IABP plus thrombus aspiration
(observation group) or only thrombus aspiration (control group)，observe the level of BNP and parameter of heart function in two groups.
Results: The level of BNP were rise in both groups for 24 hours after the operation. It was increased significantly compared with
observation group (P＜ 0. 01), And it was decreased significantly compared with control group, for 2 weeks after the operation (P ＜ 0.
01) .Compared with control group, the CI, SI and SvO2 of observation group were better for 2 weeks after the operation.Conclusion:
Combined application of IABP and thrombus aspiration may improve myocardial ischemia,coronary perfusion and heart function in acute
myocardial infarction with severe cardiac insufficiency. |
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