| 杨洁梅赵进军修春红沈景霞刘慧薛凤华.组织多普勒成像对射血分数正常的心衰患者左心功能评价[J].现代生物医学进展英文版,2012,12(3):479-482. |
| 组织多普勒成像对射血分数正常的心衰患者左心功能评价 |
| Evaluation of Left Ventricular Function by Tissue Doppler Imaging inPatients of Heart Failure with Normal Ejection Fraction |
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| DOI： |
| 中文关键词: 组织多普勒成像 左室射血分数 射学分数正常的心衰 |
| 英文关键词: Tissue Doppler Imaging (TDI) Left ventricular ejection fraction (LVEF) Heart failure with normal ejection fraction
(HFNEF) |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨组织多普勒成像（TDI）技术评价射血分数正常的心衰患者左室长轴功能特点。方法：选取30 名健康人(Ⅰ组)、
EF＞50%的心衰患者30 名（Ⅱ组）和EF<50%的心衰患者30 名（Ⅲ组)作为研究对象，采用TDI 在二尖瓣环室间隔（ivs）、侧壁（l）、
前壁(a)、后壁(p)、下壁(d)测量其Sm、DSm、IVCTm、TSm、Em、Am、IVRTm、TEm 等指标。结果：Ⅰ组、Ⅱ组、Ⅲ组DSm、Sm 逐渐减
低，（P＜0.05）；而IVCTm、TSm 逐渐升高（P＜0.05）；IVRTm、TEm 在Ⅰ组、Ⅲ组、Ⅱ组逐渐升高（P＜0.05）；DSm 及TEm 在诊断
EF＞50%心衰患者心功能的指标中ROC 曲线下面积最大，同样DSp 及TEp 在五个位点中ROC 曲线下面积最大。结论：射血分
数正常的心衰患者存在收缩减低；DSm 及TEm 是诊断EF＞50%心衰患者心功能比较有效的指标；后壁是诊断的最佳位点。 |
| 英文摘要: |
| Objective: To evaluate the variation of left ventricular function in the patients of heart failure with normal ejection
fraction by Tissue doppler imaging. Methods: 30 healthy individuals(Group Ⅰ), 30 patients of heart failure with EF＞50% (Group Ⅱ) and
30 patients with EF＜50% (Group Ⅲ) were selected as typical samples. Tissue Doppler Imaging (TDI) was used to measure the flow
velocity of 5 sites in long axis of the mitral annular systolic peak velocity (Sm), systolic displacement (DSm) , isovolumic contraction
time (IVCTm), time to systolic velocity (TSm), early diastolic velocity (Em) , peak velocity of trans-mitral flow by atrial contraction
(Am), isovolumic relaxation time (IVRTm), time to diastolic velocity (TEm). Results: The parameters Sm and DSm decreased, and
IVCTm, TSm increased gradually in GroupⅠ, Ⅱ and Ⅲ (P＜0.05). IVRTm, TEm increased gradually in Group Ⅰ, Ⅲ and Ⅱ (P＜0.05).
DSm and IVRTm had the biggest area under ROC curve respectively to evaluate left ventricular function of heart-failure patients with
EF＞50%, DSp and IVRTp had the biggest area under ROC curve respectively in the five sites. Conclusions: The patients of heart failure
with normal ejection fraction have systolic dysfunction in left ventricular long-axis. DSm and TEm are effective parameters to diagnose
left ventricular function in the patients of heart failure with EF＞50%. DSp and TEp are the optimal sites for assessing left ventricular
function in the patients of heart failure with normal ejection fraction. |
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