| 柳林1 李照玉1 纪伟2.Dynamin 在胞吞中的研究进展[J].现代生物医学进展英文版,2012,12(1):183-185. |
| Dynamin 在胞吞中的研究进展 |
| Research Progress of Dynamin in Endocytosis |
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| DOI： |
| 中文关键词: 胞吞 dynamin |
| 英文关键词: Endocytosis Dynamin |
| 基金项目: |
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| 中文摘要: |
| dynamin 家族是一类鸟苷酸三磷酸酶，是细胞在进行内呑过程中特异的一种蛋白，它参与囊泡从细胞膜上出芽和剪切的过
程。从低等生物酵母到所有高等生物都发现了dynamin 或者其同源物存在。通过对不同物种的基因组序列分析和基因克隆，发现
了三种典型dynamin 蛋白和几类同源蛋白。它们在不同的器官或者不同的亚细胞结构上行使着不同的功能。通过对dynamin 功能
域的研究，发现dynamin 的PRD 结构域能与很多蛋白相互作用。本文主要总结了dynamin 家族蛋白和与之相互作用的蛋白。 |
| 英文摘要: |
| Dynamins are large GTPases that participate in endocytosis, and are involved in the budding and scission of a wide
range of vesicles and organelles. They are found in all of species from yeast to human being. Through whole genomic analysis and positive
clone, three classic dynamin and several dynamin like proteins have been found. They play different roles in different organs or different
organelles. When studying the domains of dynamin, we notice that there are many proteins can interact with dynamin with a special domain. |
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